Evidence map›Paper›PMID 41132482›Full record

ArticleCureus2025

Gas Station Heroin: A Case Report of Tianeptine Use Disorder and a Literature Review.

Kalyan Kandra, Raghavendran Gajagowni, Gabriela A Fernandez, Natalie Polechonski, Brandon P Blewett

Abstract readCase Reports
In one paragraph

Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Kalyan KandraPsychiatry, Southern Illinois University School of Medicine, Springfield, USA.
Raghavendran GajagowniPsychiatry, North Mississippi Medical Center, Tupelo, USA.
Gabriela A FernandezPsychiatry, Southern Illinois University School of Medicine, Springfield, USA.
Natalie PolechonskiPsychiatry, Southern Illinois University School of Medicine, Springfield, USA.
Brandon P BlewettPsychiatry, Southern Illinois University School of Medicine, Springfield, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Tianeptine, an atypical antidepressant prescribed in several countries, is not approved for medical use in the United States. Despite this, it is widely available as an unregulated supplement, popularly known as "gas station heroin," contributing to a growing public health crisis characterized by dependence, severe withdrawal, and overdose. We present the case of a 22-year-old male with major depressive disorder who developed severe tianeptine use disorder. He presented with worsening depression and suicidal ideation, with his psychiatric symptoms substantially exacerbated by cycles of intoxication and withdrawal. The patient declined referral to medication-assisted treatment, highlighting ongoing barriers to care. This case underscores diagnostic challenges when psychiatric symptoms mask underlying substance use disorders and emphasizes the urgent need for clinician awareness, patient education, and regulatory action.

Indexed as

addictionantidepressantgas station heroinnootropicopioid agonistopioid use disorderssubstance use disordertianeptinetianna redzaza

Identifiers

PMID41132482
PMCPMC12542876

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.