Evidence map›Paper›PMID 41132489›Full record

ArticleFrontiers in cellular and infection microbiology2025

Microbiomics and metabolomics explored the characteristics of gut microbiota and metabolites in patients with aortic dissection.

Wenkun Liu, Qiu Lin, Huiying Zhong, Jing Liang, Binmei Liu, Yunnan Hu

Abstract read
In one paragraph

Article in Frontiers in cellular and infection microbiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Wenkun Liu *Department of Cardiology, Fujian Medical University Union Hospital, Fuzhou, China.
Qiu Lin *Department of Clinical Laboratory, Fujian Medical University Union Hospital, Fuzhou, China.
Huiying ZhongFujian Cardiovascular Medicine Center, Fuzhou, China.
Jing LiangFujian Cardiovascular Medicine Center, Fuzhou, China.
Binmei LiuFujian Cardiovascular Medicine Center, Fuzhou, China.
Yunnan HuFujian Cardiovascular Medicine Center, Fuzhou, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Aortic dissection (AD) is a serious and frequently fatal condition with highly variable presentations, which increases the difficulty of diagnosis during the incubation period. The objective of this study was to reveal the influence of gut microbiota and metabolites on the occurrence and development of AD. In the present study, a total of 132 volunteers were recruited, but only 50 met the experimental requirements (including 25 health controls and 25 patients with AD). Patients with AD showed the high levels of systolic blood pressure (SBP) and diastolic blood pressure (DBP), accompanied with aortic dilation. High-throughput sequencing revealed a reduction in the abundance of beneficial bacteria (containing

Indexed as

Aortic DissectionBacteriaGastrointestinal MicrobiomeMetabolomeMetabolomicsAdultAgedBlood PressureFemaleHigh-Throughput Nucleotide SequencingHumansMaleMiddle Agedaortic dissectiongut metabolitesgut microbiotametabolic pathwayphenotype

Identifiers

PMID41132489
PMCPMC12540387

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.