Evidence map›Paper›PMID 41132993›Full record

ArticleTranslational lung cancer research2025

Risk of conversion and severe postoperative complications in older patients with non-small cell lung cancer and a history of COVID-19: a population-based study.

Hanbo Pan, Ye Dong, Yeqin Guo, Ling Li, Wanyu Li, Jiaqi Zhang, Haizhen Jin, Weicheng Kong, Hang Chen, Zhen Ge and 19 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Translational lung cancer research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

29 authors.

Hanbo Pan *Department of Thoracic Surgical Oncology, Shanghai Lung Cancer Center, Shanghai Chest Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Ye Dong *Department of Radiology, Shanghai Chest Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Yeqin Guo *Hospital's Office, Shanghai Chest Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Ling LiDepartment of Clinical Medicine, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Wanyu LiDepartment of Integrated Traditional Chinese and Western Medicine, Shanghai Chest Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Jiaqi ZhangDepartment of Thoracic Surgical Oncology, Shanghai Lung Cancer Center, Shanghai Chest Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Haizhen JinDepartment of Central Laboratory, Shanghai Chest Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Weicheng KongDepartment of Thoracic Surgery, Putuo District People's Hospital, Zhoushan, China.
Hang ChenDepartment of Cardiothoracic Surgery, The Affiliated Lihuili Hospital of Ningbo University, Ningbo, China.
Zhen GeDepartment of Cardiothoracic Surgery, The First Affiliated Hospital of Ningbo University, Ningbo, China.
Yu TianDepartment of Thoracic Surgical Oncology, Shanghai Lung Cancer Center, Shanghai Chest Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Junwei NingDepartment of Thoracic Surgical Oncology, Shanghai Lung Cancer Center, Shanghai Chest Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Zhiyuan BaoDepartment of Emergency and Critical Care Medicine, The First People's Hospital of Fuyang Hangzhou, Hangzhou, China.
Qiyang QiuDepartment of Medicine, Shaoxing Shengzhou People's Hospital, The First Affiliated Hospital of Zhejiang University Shengzhou Branch, Shaoxing, China.
Difan ZhangDepartment of Internal Medicine, Xinhua Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Yixing TaoDepartment of Thoracic Surgical Oncology, Shanghai Lung Cancer Center, Shanghai Chest Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Fan ShenDepartment of Thoracic Surgical Oncology, Shanghai Lung Cancer Center, Shanghai Chest Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Weiqiu JinDepartment of Thoracic Surgery, Sichuan Cancer Hospital & Research Institute, School of Medicine, University of Electronic Science and Technology of China (UESTC), Chengdu, China.
Guomo RuanHospital's Office, Wenzhou People's Hospital, The Third Affiliated Hospital of Shanghai University, Wenzhou, China.
Zongxiang DuanDepartment of Thoracic Surgical Oncology, Shanghai Lung Cancer Center, Shanghai Chest Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Min ZhengDepartment of Thoracic Surgery, Shanghai Tongren Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Liang FangDepartment of Thoracic Surgical Oncology, Shanghai Lung Cancer Center, Shanghai Chest Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Chengwei ZhouDepartment of Cardiothoracic Surgery, The First Affiliated Hospital of Ningbo University, Ningbo, China.
Guodong XuDepartment of Cardiothoracic Surgery, The Affiliated Lihuili Hospital of Ningbo University, Ningbo, China.
Ming ZhangDepartment of Integrated Traditional Chinese and Western Medicine, Shanghai Chest Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Jia HuangDepartment of Thoracic Surgical Oncology, Shanghai Lung Cancer Center, Shanghai Chest Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Hui YinDepartment of Thoracic Surgery, The First Affiliated Hospital of Shaoyang University, Shaoyang, China.
Qingquan LuoDepartment of Thoracic Surgical Oncology, Shanghai Lung Cancer Center, Shanghai Chest Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Hui WangDepartment of Thoracic Surgical Oncology, Shanghai Lung Cancer Center, Shanghai Chest Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Older adult patients are more prone to long-term complications from coronavirus disease 2019 (COVID-19) and are generally more vulnerable during lung surgery compared to younger individuals. This study aimed to determine whether a past COVID-19 infection elevates surgical difficulty and risk for older adult patients with non-small cell lung cancer (NSCLC), identify high-risk post-COVID-19 subgroups, and preoperatively predict surgical difficulty and risk. Methods: Patients with clinical T1-3N1-2M0 NSCLC, aged ≥65 years, and with a history of COVID-19 (PCOV group) or without one (NCOV group) who underwent curative surgery at seven tertiary health care institutions in China between 2021 and 2024 were retrospectively included. The surgical difficulty and risk were measured according to the incidence of conversion and severe postoperative complications (Clavien-Dindo grade ≥III), respectively. Propensity-score matching (PSM) was used to mitigate patient selection bias. Prediction models were developed to preoperatively forecast the risk of conversion and severe complications. Results: PSM of the 22,101 included cases generated 7330 cases per group with well-balanced baseline characteristics. The two groups had comparable conversion rates (PCOV: 6.5% Conclusions: Past COVID-19 infection does not significantly increase surgical difficulty or risk for older adult patients with NSCLC. However, heavy smokers and those aged ≥75 years face elevated surgical risks following COVID-19 infection. The proposed preoperative prediction models can effectively forecast surgical difficulties and risks for older adult patients with NSCLC.

Indexed as

Coronavirus disease 2019 (COVID-19)elderly populationnon-small cell lung cancer (NSCLC)predictive modelsurgical difficultysurgical risk

Identifiers

PMID41132993
PMCPMC12541870

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.