Evidence map›Paper›PMID 41133091›Full record

ArticleSAGE open medicine2025

Acute heart failure in patients with hematologic malignancies: A nationwide analysis 2016-2021.

Barath Prashanth Sivasubramanian, Diviya Bharathi Ravikumar, Siva Naga S Yarrarapu, Ragavendar Saravanabavanandan, Ibthisam Ismail Sharieff, Shashvat Joshi, Deepthi Karunakar, Visalakshi Kannathal Vairavan, Indrajith Devandra Balamurugan, Umabalan Thirupathy and 3 more

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Article in SAGE open medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

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No citing paper in PubMed yet.

4 · The record

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5 · Who and what money

Authors and funding

13 authors.

Barath Prashanth SivasubramanianDepartment of Internal Medicine, Northeast Georgia Medical Center, Gainesville, GA, USA.
Diviya Bharathi RavikumarDepartment of Internal Medicine, ESIC Medical College and Postgraduate Institute of Medical Science and Research, Chennai, Tamil Nadu, India.ORCID https://orcid.org/0000-0002-6018-5647
Siva Naga S YarrarapuGeriatric Medicine, University of Texas Health Science Center at San Antonio, TX, USA.
Ragavendar SaravanabavanandanDepartment of Internal Medicine, University of Illinois College of Medicine Peoria (UICOMP), IL, USA.
Ibthisam Ismail SharieffDepartment of Internal Medicine, ESIC Medical College and Postgraduate Institute of Medical Science and Research, Chennai, Tamil Nadu, India.
Shashvat JoshiDepartment of Internal Medicine, Fudan University, Shanghai, China.
Deepthi KarunakarDepartment of Internal Medicine, Pondicherry Institute of Medical Sciences, India.
Visalakshi Kannathal VairavanInstitute of Fundamental Medicine and Biology, Kazan Federal University, Republic of Tatarstan.
Indrajith Devandra BalamuruganSchool of Basic Medical Sciences, Tianjin Medical University, Heping District, P.R. China.
Umabalan ThirupathyDepartment of Medicine, Saint Vincent Hospital, Keene, NH, USA.
Vikramaditya Samala VenkataHospital Medicine Division, Cheshire Medical Center/Dartmouth-Hitchcock, Keene, NH, USA.
Yash GargNortheast Georgia Medical Center, New York, NY, USA.
Aditya Kumar GhoshDivision of General Internal Medicine, Mayo Clinic, Rochester, MN, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Acute heart failure affects ~9% of patients with hematological malignancies. This study aimed to evaluate the impact of acute heart failure on in-hospital mortality among patients with hematological malignancies and to identify independent predictors of mortality in this population. Methods: The National Inpatient Sample (2016-2021) was queried for adults (⩾18 years of age) with hematological malignancies and those who experienced in-hospital mortality. Among these, we identified patients who were hospitalized with a diagnosis of acute heart failure. Univariate analysis and multivariate regression were employed to analyze the mortality risk. A Results: Among 40,246 patients with hematological malignancies who died in the hospital, the univariate analysis showed a higher in-hospital mortality in the acute heart failure cohort compared to the non-acute heart failure group (8.08% versus 4.52%, Conclusion: Acute heart failure in patients with hematological malignancies was associated with poor outcomes in the presence of severe sepsis, organ dysfunction, and the need for mechanical ventilation. Close monitoring and a multidisciplinary team approach are recommended to optimize the treatment plan for this population.

Indexed as

AMLBCR/ABLCLLCMLheart failureleukemiamortalitymultiple myelomasepsis

Identifiers

PMID41133091
PMCPMC12541186

What Socratic holds

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.