ReviewFrontiers in medicine2025
Clinical characteristics and risk factor analysis of overlapping syndromes of COPD-OSA with metabolic syndrome in middle-to-high altitude areas.
Review in Frontiers in medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 2 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed.
- Precision Medicine in Overlap Syndrome (COPD-Obstructive Sleep Apnea): From Phenotypes and Endotypes to Treatable Traits.Advances in respiratory medicine · 2026Review
- COPD-OSA overlap syndrome: inflammatory and oxidative stress mechanisms, biomarkers, and clinical implications.Frontiers in medicine · 2026Review
Corrections and comments
- Erratum issued
Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Objective: To investigate the clinical characteristics and risk factors of overlap syndrome (OVS) patients with metabolic syndrome (Mets) in middle-high altitude areas. Methods: A retrospective analysis was performed on adult (≥40 years) OVS patients and healthy controls from Qinghai Provincial People's Hospital (January 2017-January 2024), including general and laboratory data. Results: 1. OVS patients had a higher rate of Diabetes, Hypertension, and Pulmonary Hypertension than healthy individuals; 2. OVS patients had significantly higher levels of inflammatory markers, hematologic, and lipid than Healthy individuals; 3. The proportion of OVS patients who also had Mets was 55.24%; 4. Compared to OVS patients without Mets, OVS patients with Mets had significantly higher levels of neutrophils, hemoglobin, red blood cell distribution width, C-reactive protein, NHR, and NLR, as well as a higher percentage of time with pulse oxygen saturation (SpO Conclusion: Over half of middle-high altitude OVS patients have Mets, with higher rates at higher altitudes. Hypoxia may drive OVS-Mets comorbidity, while inflammation appears less significant.
Indexed as
Identifiers
What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.