Evidence mapPaperPMID 41133233Full record

ReviewFrontiers in endocrinology2025

Environmental and social determinants of cardiovascular risk in women with type 2 diabetes: a life-course perspective.

Camilla Cocchi, Valentina Selleri, Giada Zanini, Federica Moscucci, Susanna Sciomer, Sabina Gallina, Milena Nasi, Giovambattista Desideri, Marcello Pinti, Claudio Borghi and 1 more

Abstract readReview
In one paragraph

Review in Frontiers in endocrinology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Pregnancy as a Window for Hypertension and Cardiovascular Prevention in Women: A Life-Course Perspective Based on the 2025 ESC Guidelines.High blood pressure & cardiovascular prevention : the official journal of the Italian Society of Hypertension · 2026
    Review
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Camilla Cocchi *Department of Ageing, Orthopedics and Rheumatology, University "Cattolica del Sacro Cuore", Rome, Italy.
Valentina Selleri *Department of Life Sciences, University of Modena and Reggio Emilia, Modena, Italy.
Giada ZaniniDepartment of Life Sciences, University of Modena and Reggio Emilia, Modena, Italy.
Federica MoscucciAzienda Ospedaliera Universitaria Policlinico Umberto I, Geriatric Unit, Rome, Italy.
Susanna Sciomer"Sapienza" University of Rome, Rome, Italy.
Sabina GallinaNational Institute for Cardiovascular Research (INRC), Bologna, Italy.
Milena NasiDepartment of Surgical, Medical and Dental Department of Morphological Sciences related to Transplant, Oncology and Regenerative Medicine, University of Modena and Reggio Emilia, Modena, Italy.
Giovambattista DesideriDepartment of Clinical and Internal Medicine, Anesthesiology and Cardiovascular Sciences, "Sapienza" University of Rome, Rome, Italy.
Marcello PintiNational Institute for Cardiovascular Research (INRC), Bologna, Italy.
Claudio BorghiDepartment of Medical and Surgical Sciences Alma Mater Studiorum University-IRCCS AOU S. Orsola-Malpighi, Bologna, Italy.
Anna Vittoria MattioliNational Institute for Cardiovascular Research (INRC), Bologna, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Cardiovascular disease (CVD) remains the leading cause of morbidity and mortality among women with type 2 diabetes (T2DM). The interplay between sex-specific biological factors, social determinants, and environmental exposures amplifies cardiometabolic risk across the female life course. Objectives: This manuscript explores how socioeconomic disparities, environmental pollution, chronic stress, food insecurity, and climate change synergistically increase the burden of T2DM and cardiovascular complications in women, and reviews potential preventive interventions including dietary strategies. Methods: A comprehensive narrative review was conducted, synthesizing current evidence on the exposome, social inequities, environmental insults, and evidence-based lifestyle interventions that contribute to or mitigate the development and progression of T2DM and CVD in women. Results: Lower socioeconomic status, limited education, housing instability, and inadequate access to healthcare and nutritious foods profoundly affect T2DM management and CVD prevention in women. Concurrently, exposure to air pollutants (PM Conclusion: Effective cardiovascular prevention in women with T2DM requires a life-course approach that integrates biological transitions with environmental and social determinants to deliver sex-sensitive, stage-specific strategies.

Indexed as

Cardiovascular DiseasesDiabetes Mellitus, Type 2Environmental ExposureSocial Determinants of HealthClimate ChangeFemaleHeart Disease Risk FactorsHumansRisk Factorscardiovascular healthchronic stressclimate changediabetes mellitusenvironmental pollutionsocioeconomic determinantswomen

Identifiers

PMID41133233
PMCPMC12540180

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.