Evidence map›Paper›PMID 41133628›Full record

ArticleNeuroSci2025

The Effect of

Alfonso Mata-Bermudez, Ricardo Trejo-Chávez, Marina Martínez-Vargas, Adán Pérez-Arredondo, Araceli Diaz-Ruiz, Camilo Rios, Héctor Alonso Romero-Sánchez, María de Los Ángeles Martínez-Cárdenas, Perla Ugalde-Muñiz, Roxana Noriega-Navarro and 1 more

Abstract read
In one paragraph

Article in NeuroSci, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Alfonso Mata-BermudezDepartamento de Fisiología, Facultad de Medicina, Universidad Nacional Autónoma de México, Mexico City 04510, Mexico.ORCID 0000-0002-2234-7019
Ricardo Trejo-ChávezDepartamento de Fisiología, Facultad de Medicina, Universidad Nacional Autónoma de México, Mexico City 04510, Mexico.
Marina Martínez-VargasDepartamento de Fisiología, Facultad de Medicina, Universidad Nacional Autónoma de México, Mexico City 04510, Mexico.
Adán Pérez-ArredondoDepartamento de Fisiología, Facultad de Medicina, Universidad Nacional Autónoma de México, Mexico City 04510, Mexico.ORCID 0000-0002-0479-6734
Araceli Diaz-RuizDepartamento de Neuroquímica, Instituto Nacional de Neurología y Neurocirugía Manuel Velasco Suarez, Mexico City 14269, Mexico.ORCID 0000-0002-1481-0966
Camilo RiosInstituto Nacional de Rehabilitación, Luis Guillermo Ibarra Ibarra, Mexico City 14389, Mexico.
Héctor Alonso Romero-SánchezDepartamento de Atención a la Salud, Universidad Autónoma Metropolitana Unidad Xochimilco, Mexico City 04510, Mexico.
María de Los Ángeles Martínez-CárdenasDepartamento de Atención a la Salud, Universidad Autónoma Metropolitana Unidad Xochimilco, Mexico City 04510, Mexico.
Perla Ugalde-MuñizDepartamento de Fisiología, Facultad de Medicina, Universidad Nacional Autónoma de México, Mexico City 04510, Mexico.
Roxana Noriega-NavarroDepartamento de Fisiología, Facultad de Medicina, Universidad Nacional Autónoma de México, Mexico City 04510, Mexico.ORCID 0000-0003-4724-569X
Luz NavarroDepartamento de Fisiología, Facultad de Medicina, Universidad Nacional Autónoma de México, Mexico City 04510, Mexico.ORCID 0000-0002-5519-0871

Funding

DGAPA, UNAM PAPIIT IN228223
6 · The paper itself

Abstract

Traumatic brain injury (TBI), even when mild, has been associated with the presence of depression. Depression is a mood disorder characterized by persistent negative thoughts and sadness and is challenging to treat due to the multiple mechanisms involved in its pathophysiology, including increased nitric oxide (NO) levels. There are no completely safe and effective pharmacological strategies to treat this disorder.

Indexed as

depressionhead injuryMucuna pruriensnitric oxideoxidative stress

Identifiers

PMID41133628
PMCPMC12551065

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.