ArticleThoracic research and practice2025
Long-term Effect of Pulmonary Rehabilitation in Pulmonary Tuberculosis Patients.
Article in Thoracic research and practice, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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6 authors.
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Abstract
objectivePost-pulmonary tuberculosis (post-PTB) sequelae, including impaired lung function, reduced exercise capacity, and diminished quality of life (QoL), pose significant challenges even after successful anti-tuberculosis treatment. While pulmonary rehabilitation (PR) is an established intervention for chronic respiratory diseases, its long-term effectiveness in post-PTB patients is not well-documented. This study aimed to evaluate the long-term impact of an 8-week outpatient PR program on respiratory function, exercise performance, and QoL in post-PTB patients. MATERIAL AND
methodsIn a randomized controlled trial, 90 post-PTB patients aged ≥18 years were allocated to either the PR group or a control group. The PR program included supervised endurance and resistance training, breathing exercises, and patient education, delivered over 8 weeks. Primary outcomes, including the 6-minute walk distance (6MWD), Saint George's Respiratory Questionnaire (SGRQ), and pulmonary function tests, were assessed at baseline, immediately post-intervention, and at 12 months. Data were analyzed using repeated measures ANOVA.
resultsThe PR group demonstrated significant and sustained improvements across all measures. The 6MWD increased by 217 meters post-PR and remained 143 meters higher at 12 months (P < 0.05). SGRQ scores showed a 28-point reduction post-PR and a 32-point reduction at 12 months (P < 0.05). FEV1 improved by 41% post-PR, and by 45% at 12 months (P < 0.05). No significant changes were observed in the control group.
conclusionAn 8-week PR program delivers long-term benefits in respiratory function, exercise capacity, and QoL in post-PTB patients. Incorporating PR into post-PTB care is a promising strategy to mitigate chronic sequelae and enhance patient outcomes.
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