ArticleAbdominal radiology (New York)2026
2D-SWE in metabolic syndrome: beyond MASLD, interrrogating the pancreas.
Article in Abdominal radiology (New York), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
purposeThe purpose of this study was to evaluate hepatic and pancreatic steatosis on grey-scale ultrasound and assess its association with hepatic and pancreatic stiffness using ultrasound 2D-shear wave elastography (2D-SWE) in patients with metabolic syndrome (MS).
methodsOne hundred and thirty-one adult patients with metabolic syndrome were included in the study. Grey scale ultrasound of liver and pancreas was performed to evaluate grades of hepatic steatosis (HS) and pancreatic steatosis (PS) respectively. Subsequently, 2D-SWE was performed to obtain liver and pancreatic stiffness in kPa and m/s. Grades of HS and PS were correlated with body mass index (BMI), biochemical parameters, hepatic and pancreatic stiffness values.
resultsModerate correlation was found between HS grade and BMI, while the correlation of PS grade with BMI was poor. On SWE, hepatic and pancreatic stiffness showed strong and moderate correlation with BMI, respectively. Among biochemical parameters, triglycerides showed highest correlation with HS grade and hepatic stiffness, while fasting blood glucose showed highest correlation with PS grade and pancreatic stiffness. The stiffness values of both organs showed statistically significant difference in participant groups with and without steatosis (p < 0.001). Mean hepatic and pancreatic stiffness values showed strong positive correlation with grade of HS (Ʈ=0.84) and PS (Ʈ=0.82), respectively.
conclusionMetabolic syndrome is associated with both hepatic and pancreatic steatosis with consequent increase in hepatic and pancreatic stiffness values respectively. These values show positive correlation with the grade of steatosis. 2D-SWE along with biochemical parameters, can be utilized in the screening of MS patients for early detection and surveillance of further disease progression to prevent potential complications.
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