Evidence mapPaperPMID 41134513Full record

ReviewHeart failure reviews2025

Echocardiographic monitoring in cancer therapy: clinical guidance for cardiologists and oncologists.

Simona Sperlongano, Giuseppe Verde, Natale Guarnaccia, Felice Gragnano, Giovanni Benfari, Vincenzo De Sio, Federica Ilardi, Matteo Lisi, Alessandro Malagoli, Giulia Elena Mandoli and 6 more

Abstract readReview
In one paragraph

Review in Heart failure reviews, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Simona SperlonganoDivision of Cardiology, Department of Translational Medical Sciences, University of Campania Luigi Vanvitelli, Naples, Italy.
Giuseppe Verde *Division of Cardiology, Department of Translational Medical Sciences, University of Campania Luigi Vanvitelli, Naples, Italy.
Natale Guarnaccia *Division of Cardiology, Department of Translational Medical Sciences, University of Campania Luigi Vanvitelli, Naples, Italy.
Felice GragnanoDivision of Cardiology, Department of Translational Medical Sciences, University of Campania Luigi Vanvitelli, Naples, Italy.
Giovanni BenfariSection of Cardiology, Department of Medicine, University of Verona, Verona, Italy.
Vincenzo De SioDivision of Cardiology, Department of Translational Medical Sciences, University of Campania Luigi Vanvitelli, Naples, Italy.
Federica IlardiDepartment of Advanced Biomedical Sciences, University of Naples Federico II, Naples, Italy.
Matteo LisiDepartment of Cardiovascular Disease - AUSL Romagna, Division of Cardiology, Ospedale S. Maria Delle Croci, Ravenna, Italy.
Alessandro MalagoliDivision of Cardiology, Nephro-Cardiovascular Department, Baggiovara Hospital, University of Modena and Reggio Emilia, Modena, Italy.
Giulia Elena MandoliDepartment of Medical Biotechnologies, Division of Cardiology, University of Siena, Siena, Italy.
Maria Concetta PastoreDepartment of Medical Biotechnologies, Division of Cardiology, University of Siena, Siena, Italy.
Ciro SantoroDepartment of Pharmacy, and Health and Nutrition Sciences, University of Calabria, Cosenza, Italy.
Matteo CameliDepartment of Medical Biotechnologies, Division of Cardiology, University of Siena, Siena, Italy.
Giovanni CimminoDivision of Cardiology, Department of Translational Medical Sciences, University of Campania Luigi Vanvitelli, Naples, Italy.
Paolo CalabròDivision of Cardiology, Department of Translational Medical Sciences, University of Campania Luigi Vanvitelli, Naples, Italy. paolo.calabro@unicampania.it.
Antonello D'AndreaDepartment of Cardiology, Umberto I Hospital, Nocera Inferiore, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Transthoracic echocardiography has a central role in the diagnosis and monitoring of cancer therapy-related cardiac dysfunction, offering a reliable, non-invasive, and cost-effective tool for the early detection of myocardial damage and the timely and effective management of cardiotoxicity. This review provides a practical and comprehensive framework for the echocardiographic assessment of oncology patients, focusing on both traditional and emerging ultrasound parameters of left and right ventricular function, and their diagnostic and prognostic value in the field of cardio-oncology. Moreover, the review discusses key aspects of pericardial disease, valvular heart disease, and intracardiac masses, which may be consequences of cancer therapy or tumor progression. Finally, the role of multimodal imaging, in particular cardiac magnetic resonance and computed tomography, is examined, especially in selected cases to supplement echocardiographic findings or when echocardiography presents limitations. Based on current guidelines and clinical experience, this review aims to provide both cardiologists and oncologists with a practical tool for interpreting echocardiographic reports in cancer patients. Additionally, a therapeutic algorithm is proposed to guide decisions on cancer treatment management and timely initiation of cardioprotective strategies in selected contexts. Close collaboration between cardiologists and oncologists remains essential to reduce cancer patients' cardiovascular risk, allowing them to access the best possible treatment and optimize outcomes by balancing anticancer therapy efficacy with cardiovascular safety.

Indexed as

Antineoplastic AgentsCardiologistsEchocardiographyHeart DiseasesNeoplasmsOncologistsCardiotoxicityHumansAntineoplastic AgentsCancer therapy-related cardiac dysfunctionCardio-oncologyLeft ventricular functionRight ventricular functionTransthoracic echocardiography

Identifiers

PMID41134513
PMCPMC12618327

What Socratic holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.