Evidence map›Paper›PMID 41134634›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2025

Nanomaterial-induced mitochondrial biogenesis enhances intercellular mitochondrial transfer efficiency.

John Soukar, Kanwar Abhay Singh, Ari Aviles, Sarah Hargett, Harman Kaur, Samantha Foster, Shounak Roy, Feng Zhao, Vishal M Gohil, Irtisha Singh and 1 more

Abstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. ROS-Balancing MXene/MoSeSmall (Weinheim an der Bergstrasse, Germany) · 2026
    Article
  3. Review
  4. Review
  5. Review
  6. Review
  7. Review
  8. Nanomaterial-induced mitochondrial biogenesis enhances intercellular mitochondrial transfer efficiency.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

John SoukarInterdisiplinary program in Genetics and Genomics, College of Agriculture and Life Sciences, Texas A&M University, College Station, TX 77843.ORCID 0000-0002-1175-2895
Kanwar Abhay SinghDepartment of Biomedical Engineering, College of Engineering, Texas A&M University, College Station, TX 77843.ORCID 0000-0001-9704-0495
Ari AvilesInterdisiplinary program in Genetics and Genomics, College of Agriculture and Life Sciences, Texas A&M University, College Station, TX 77843.ORCID 0000-0002-0839-8426
Sarah HargettDepartment of Biomedical Engineering, College of Engineering, Texas A&M University, College Station, TX 77843.ORCID 0000-0002-5389-6344
Harman KaurDepartment of Biochemistry and Biophysics, College of Agriculture and Life Sciences, Texas A&M University, College Station, TX 77843.ORCID 0000-0002-7536-9991
Samantha FosterInterdisiplinary program in Genetics and Genomics, College of Agriculture and Life Sciences, Texas A&M University, College Station, TX 77843.ORCID 0009-0005-9599-5219
Shounak RoyDepartment of Biomedical Engineering, College of Engineering, Texas A&M University, College Station, TX 77843.
Feng ZhaoDepartment of Biomedical Engineering, College of Engineering, Texas A&M University, College Station, TX 77843.ORCID 0000-0003-4138-9027
Vishal M GohilInterdisiplinary program in Genetics and Genomics, College of Agriculture and Life Sciences, Texas A&M University, College Station, TX 77843.ORCID 0000-0002-9920-2563
Irtisha SinghInterdisiplinary program in Genetics and Genomics, College of Agriculture and Life Sciences, Texas A&M University, College Station, TX 77843.ORCID 0000-0002-9460-3587
Akhilesh K GaharwarInterdisiplinary program in Genetics and Genomics, College of Agriculture and Life Sciences, Texas A&M University, College Station, TX 77843.ORCID 0000-0002-0284-0201

Funding

Mitochondrial Copper BiologyR35GM152102 · NIGMS · TEXAS A&M AGRILIFE RESEARCH · PI Vishal Mahendrasingh Gohil · 2024 to 2026
$1.7M
Osteoinductive Nanosilicate-Based Biomaterials for In Situ Craniomaxillofacial Bone RegenerationR01DE032031 · NIDCR · TEXAS ENGINEERING EXPERIMENT STATION · PI CARL A. GREGORY, Akhilesh K. Gaharwar · 2024 to 2026
$1.7M
Investigating the role Ikaros variants in multiple myeloma pathophysiology and drug sensitivityR01CA282251 · NCI · TEXAS A&M UNIVERSITY HEALTH SCIENCE CTR · PI Irtisha Singh · 2024 to 2026
$1.1M
Cancer Prevention and Research Institute of Texas (CPRIT) RP230204Center for Strategic Scientific Initiatives, National Cancer Institute (CSSI) CA282251DOD | MHS | Congressionally Directed Medical Research Programs (CDMRP) W81XWH2210932HHS | NIH | National Institute of Dental and Craniofacial Research (NIDR) DE032031HHS | NIH | National Institute of General Medical Sciences (NIGMS) GM152102NCI NIH HHS R01 CA282251NIDCR NIH HHS R01 DE032031NIGMS NIH HHS R35 GM152102Welch Foundation (The Welch Foundation) A-1810
6 · The paper itself

Abstract

Intercellular mitochondrial transfer, the spontaneous exchange of mitochondria between cells, is a recently described phenomenon crucial for cellular repair, regeneration, and disease management. Enhancing this natural process holds promise for developing novel therapies targeting diseases associated with mitochondrial dysfunction. Here, we introduce a nanomaterial-based approach employing molybdenum disulfide (MoS

Indexed as

DisulfidesMitochondriaMolybdenumNanostructuresOrganelle BiogenesisAdenosine TriphosphateHumansAdenosine TriphosphateDisulfidesMolybdenummolybdenum disulfidebiomaterialscellular medicinemitochondriananomaterialsregenerative medicine

Identifiers

PMID41134634
PMCPMC12582283

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.