Evidence map›Paper›PMID 41137868›Full record

ReviewNaunyn-Schmiedeberg's archives of pharmacology2026

Sex differences in coronary artery disease.

Lena Marie Seegers

Abstract readReview
In one paragraph

Review in Naunyn-Schmiedeberg's archives of pharmacology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author.

Lena Marie SeegersDepartment of Cardiology and Angiology, Frankfurt University Hospital, Theodor-Stern-Kai 7, 60590, Frankfurt, Germany. lena.seegers@unimedizin-ffm.de.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Myocardial infarction is the leading cause of death worldwide in men and in women. Nevertheless, cardiovascular diseases in women are still understudied, underdiagnosed and undertreated leading to poor outcomes and higher mortality rates. Important sex differences exist in coronary artery disease with a higher symptom burden, delayed presentation and treatment of women in the emergency department and more non-obstructive coronary artery disease on angiogram. Sex hormones influence hemostasis and platelet function, and women suffer more from major bleeding complications after coronary interventions. Moreover, cholesterol levels increase with age particularly in women and sex hormones might play an important role in the development and progression of atherosclerosis with an increasing cardiovascular risk for women after menopause. Women also have other unique sex-specific risk factors such as hypertensive disorders of pregnancy that are contributing to an increased risk of myocardial infarction. Therefore, pharmacological therapies regarding primary or secondary prevention of coronary artery disease need to address sex differences to improve female outcome in the future. This review highlights these differences and specific risk factors in women to consider in pharmacological management of coronary artery disease.

Indexed as

Coronary Artery DiseaseSex CharacteristicsAnimalsFemaleGonadal Steroid HormonesHumansMaleRisk FactorsSex FactorsGonadal Steroid HormonesAtherosclerosisCoronary artery diseaseMyocardial infarctionSex differencesWomen’s health

Identifiers

PMID41137868
PMCPMC13046606

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.