Evidence map›Paper›PMID 41137997›Full record

ArticleNeurochemical research2025

Oxidative Stress Induces the Phosphorylation of NAD

Johanna Elisabeth Willker, Patrick Watermann, Ralf Dringen

Abstract read
In one paragraph

Article in Neurochemical research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Johanna Elisabeth WillkerCentre for Biomolecular Interactions Bremen, Faculty 2 (Biology/Chemistry), University of Bremen, P.O. Box 330440, 28334, Bremen, Germany.ORCID http://orcid.org/0009-0000-9918-0723
Patrick WatermannCentre for Biomolecular Interactions Bremen, Faculty 2 (Biology/Chemistry), University of Bremen, P.O. Box 330440, 28334, Bremen, Germany.ORCID http://orcid.org/0000-0003-2811-8118
Ralf DringenCentre for Biomolecular Interactions Bremen, Faculty 2 (Biology/Chemistry), University of Bremen, P.O. Box 330440, 28334, Bremen, Germany. ralf.dringen@uni-bremen.de.ORCID http://orcid.org/0000-0001-7869-1305

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Astrocytes have important functions in the metabolism and antioxidative defence of the brain. Three redox pairs and the ratio of the reduced and oxidized partners in each pair are essential for astrocytic redox metabolism, GSx (glutathione (GSH) plus glutathione disulfide (GSSG)), NADx (NADH plus NAD

Indexed as

AstrocytesNADNADPOxidative StressPhosphotransferases (Alcohol Group Acceptor)AnimalsCells, CulturedPhosphorylationRatsRats, WistarNADNAD kinaseNADPPhosphotransferases (Alcohol Group Acceptor)AstrocytesGlutathioneNAD kinaseNicotinamide coenzymesOxidative stress

Identifiers

PMID41137997
PMCPMC12553597

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.