Evidence map›Paper›PMID 41139743›Full record

ArticleJournal of medical systems2025

Universal Atrial Fibrillation Screening Using Electrocardiographic Artificial Intelligence: A Cost-Effective Approach in Rural Communities.

Wei-Ting Liu, Chin-Sheng Lin, Chin Lin, Tsung-Kun Lin, Wen-Yu Lin, Chiao-Chin Lee, Chiao-Hsiang Chang, Chien-Sung Tsai, Yi-Jen Hung, Ping-Hsuan Hsieh

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Article in Journal of medical systems, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Wei-Ting LiuDivision of Cardiology, Department of Internal Medicine, Tri-Service General Hospital, National Defense Medical University, Taipei, Taiwan.
Chin-Sheng LinDivision of Cardiology, Department of Internal Medicine, Tri-Service General Hospital, National Defense Medical University, Taipei, Taiwan.
Chin LinArtificial Intelligence of Things Center, Tri-Service General Hospital, National Defense Medical University, Taipei, Taiwan.
Tsung-Kun LinDepartment of Pharmacy, Tri-Service General Hospital, National Defense Medical University, Taipei, Taiwan.
Wen-Yu LinDivision of Cardiology, Department of Internal Medicine, Tri-Service General Hospital, National Defense Medical University, Taipei, Taiwan.
Chiao-Chin LeeDivision of Cardiology, Department of Internal Medicine, Tri-Service General Hospital, National Defense Medical University, Taipei, Taiwan.
Chiao-Hsiang ChangDivision of Cardiology, Department of Internal Medicine, Tri-Service General Hospital, National Defense Medical University, Taipei, Taiwan.
Chien-Sung TsaiDivision of Cardiovascular Surgery, Department of Surgery, Tri-Service General Hospital, National Defense Medical University, Taipei, Taiwan.
Yi-Jen HungDivision of Endocrinology and Metabolism, Department of Internal Medicine, Tri-Service General Hospital, National Defense Medical University, Taipei, Taiwan.
Ping-Hsuan HsiehCollege of Pharmacy, National Defense Medical University, Taipei, Taiwan. pinghsuan.h@mail.ndmctsgh.edu.tw.

Funding

National Science and Technology Council NSTC 114-2314-B-016-014Tri-Service General Hospital TSGH-D-113054
6 · The paper itself

Abstract

Atrial fibrillation (AF) significantly contributes to the incidence of strokes. Screening for AF enhances its detection and effective management. However, universal AF screening in rural areas poses a challenge. This study evaluates the cost-effectiveness of artificial intelligence-enabled 12-lead electrocardiography (AI-ECG) model for AF screening in rural communities.This cost-effectiveness analysis targeted individuals aged 65 or older, employing a lifelong decision analytic Markov model. AI-ECG model, trained and validated at three Taiwanese hospitals with 285,108 patients, achieved sensitivities of 97.8% and specificities of 99.1%. The study incorporated costs and efficacy of anticoagulant treatments, health status utilities, and clinical variables, derived from literature and Taiwan's epidemiological data. Outcomes were expressed in US dollars per quality-adjusted life year (QALY). The base-case analysis contrasted AI-ECG screening performed by nurses and physician evaluations using standard 12-lead ECGs against no screening, incorporating uncertainty through probabilistic sensitivity analysis. Results were compared with one GDP per capita in Taiwan (≈$32,327 per QALY), a commonly cited willingness-to-pay (WTP) benchmark.Both AI-ECG and physician-led screenings were costlier yet more effective compared with no screening. Although both methods showed comparable effectiveness in detecting AF and in QALYs gained, AI-ECG screening was less expensive ($141 versus $196). Based on 5,000 Monte Carlo simulations, AI-based screening is more cost-effective at lower thresholds ($4,349 to $6,132 per QALY), while physician-led screening becomes preferable beyond $6,132 per QALY. Both strategies remained cost-effective relative to the WTP benchmark. Sensitivity analyses further identified the referral rate following a positive AI-ECG screening as a critical determinant of its cost-effectiveness.AI-ECG screening for AF is a cost-effective alternative, particularly suitable for areas with limited medical resources.

Indexed as

Artificial IntelligenceAtrial FibrillationElectrocardiographyMass ScreeningAgedCost-Benefit AnalysisFemaleHumansMaleMarkov ChainsQuality-Adjusted Life YearsRural PopulationSensitivity and SpecificityTaiwanArtificial intelligenceAtrial fibrillationCost-effectiveness analysisElectrocardiogramRural areaSystematic screening

Identifiers

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.