Evidence mapPaperPMID 41139760Full record

Trial reportChinese journal of integrative medicine2025

Wenyang Lishui Formula Ameliorates Symptoms of Ovarian Hyperstimulation Syndrome: A Prospective Cohort Study.

Xi-Yan Xin, Yang Wang, Hua Zhang, Jia-Cheng Zhang, Meng-Jie Fan, Xi Zhang, Jing Xu, Yang Ye, Xin-Yu Hao, Dong Li and 1 more

Abstract readRandomized Controlled Trial
PubMed Publisher
In one paragraph

Trial report in Chinese journal of integrative medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

11 authors.

Xi-Yan XinDepartment of Traditional Chinese Medicine, Peking University Third Hospital, Beijing, 100191, China.
Yang WangState Key Laboratory of Female Fertility Promotion, Center for Reproductive Medicine, Department of Obstetrics and Gynecology, Peking University Third Hospital, Beijing, 100191, China.
Hua ZhangResearch Center of Clinical Epidemiology, Peking University Third Hospital, Beijing, 100191, China.
Jia-Cheng ZhangDepartment of Traditional Chinese Medicine, Peking University Third Hospital, Beijing, 100191, China.
Meng-Jie FanCenter for Reproductive Medicine, Department of Obstetrics and Gynecology, Peking University Third Hospital, Beijing, 100191, China.
Xi ZhangCenter for Reproductive Medicine, Department of Obstetrics and Gynecology, Peking University Third Hospital, Beijing, 100191, China.
Jing XuDepartment of Traditional Chinese Medicine, Peking University Third Hospital, Beijing, 100191, China.
Yang YeDepartment of Traditional Chinese Medicine, Peking University Third Hospital, Beijing, 100191, China.
Xin-Yu HaoDepartment of Traditional Chinese Medicine, Peking University Third Hospital, Beijing, 100191, China.
Dong LiDepartment of Traditional Chinese Medicine, Peking University Third Hospital, Beijing, 100191, China. lidong6512@sina.com.
Rong LiState Key Laboratory of Female Fertility Promotion, Center for Reproductive Medicine, Department of Obstetrics and Gynecology, Peking University Third Hospital, Beijing, 100191, China. roseli001@sina.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo study the clinical efficacy of Wenyang Lishui Formula (WYLSF) in preventing ovarian hyperstimulation syndrome (OHSS) and explore the suitable range of estradiol (E

methodsPart I: eligible patients at high risk for OHSS undergoing ovulation induction between January and December, 2023 were randomized into 2 groups based on the actual treatment. The treatment group received 200 mL WYLSF formula twice daily for 5 days after oocyte retrieval in a combination of lifestyle coaching (LC) intervention including regular diet and exercise, whereas the LC group received LC intervention alone. The incidence of OHSS, OHSS self-assessment scales, changes in E

resultsA total of 120 patients were included in the Part I analysis. The treatment group (60 cases) showed a significant reduction in the incidence, duration, and severity of abdominal distension, as well as the incidence of vomiting compared with the LC group (P<0.05). The post-retrieval E

conclusionsWYLSF can effectively reduce specific symptoms in high-risk OHSS patients after ovulation induction and significantly lower E

Indexed as

Drugs, Chinese HerbalOvarian Hyperstimulation SyndromeAdultChorionic GonadotropinEstradiolFemaleHumansOvulation InductionProspective StudiesChorionic GonadotropinDrugs, Chinese HerbalEstradiolChinese medicineestradiolovarian hyperstimulation syndromepreventive effectprospective cohort studyWenyang Lishui Formula

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.