ReviewJournal of cellular and molecular medicine2025
Immune Cell Dynamics in Cardiac Diseases: Insights From Single-Cell Sequencing.
Review in Journal of cellular and molecular medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed, 1 synthesis or guideline pooled it.
- SIRT3 in post-myocardial infarction macrophage reprogramming: linking mitochondrial fitness to inflammation resolution and repair.Frontiers in immunology · 2026Pooled it
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
Abstract
Immune cell-mediated immune-inflammatory responses play a key role in the development of cardiac diseases. To study cardiac health and the underlying pathophysiological mechanisms, researchers must thoroughly understand immune cell functions and characteristics. However, the complex cellular heterogeneity and inter-cellular interactions remain largely unexplored. Single-cell sequencing, a high-throughput technique for sequencing genomes and transcriptomes at the individual cell level, not only enables the discovery of new cell types but also provides a detailed assessment of cellular heterogeneity and reveals each cell's unique contribution to disease. This technological advancement has significantly impacted cardiovascular research, reshaping our understanding of immune cells' roles in the development of cardiac diseases. Therefore, it is crucial to comprehensively summarise the plasticity, heterogeneity, infiltration patterns and functional roles of immune cells using single-cell sequencing, focusing on the dynamic regulation of immuno-inflammatory responses across various cardiac diseases to develop more precise therapeutic targets for cardiac diseases.
Indexed as
Identifiers
What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.