Evidence map›Paper›PMID 41141737›Full record

ArticleACS omega2025

A Promising Anti-dengue Virus Carboxylated-Sesquiterpene Lactone from

Jimena Borgo, Alejandro Rodríguez-Martínez, Mariel S Wagner, Augusto E Bivona, Claudia S Sepúlveda, César A N Catalán, Horacio Pérez-Sánchez, Valeria P Sülsen

Abstract read
In one paragraph

Article in ACS omega, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Jimena BorgoInstituto de Química y Metabolismo del Fármaco, (IQUIMEFA) CONICET-Universidad de Buenos Aires; Cátedra de Farmacognosia, Facultad de Farmacia y Bioquímica, Universidad de Buenos Aires, C1113AAD Buenos Aires, Argentina.
Alejandro Rodríguez-MartínezStructural Bioinformatics and High Performance Computing Research Group (BIO-HPC), HiTech Innovation Hub, Universidad Católica San Antonio de Murcia (UCAM), 30107 Murcia, Spain.ORCID https://orcid.org/0000-0002-1251-8072
Mariel S WagnerLaboratorio de Estrategias Antivirales, Departamento de Química Biológica, Facultad de Ciencias Exactas y Naturales, Universidad de Buenos Aires, C1428EGA Buenos Aires, Argentina.
Augusto E BivonaInstituto de Estudios de la Inmunidad Humoral Prof. Ricardo A. Margni (IDEHU), (Universidad de Buenos Aires- CONICET), Buenos Aires C1113AAD, Argentina; Cátedra de Inmunología, Facultad de Farmacia y Bioquímica, Universidad de Buenos Aires, C1113AAD Buenos Aires, Argentina.
Claudia S SepúlvedaInstituto de Química Biológica de la Facultad de Ciencias Exactas y Naturales (IQUIBICEN), CONICET-Universidad de Buenos Aires, C1428EGA Buenos Aires, Argentina.
César A N CatalánInstituto de Química Orgánica, Facultad de Bioquímica, Química y Farmacia, Universidad Nacional de Tucumán, T4000INI San Miguel de Tucumán, Tucumán, Argentina.
Horacio Pérez-SánchezStructural Bioinformatics and High Performance Computing Research Group (BIO-HPC), HiTech Innovation Hub, Universidad Católica San Antonio de Murcia (UCAM), 30107 Murcia, Spain.ORCID https://orcid.org/0000-0003-4468-7898
Valeria P SülsenInstituto de Química y Metabolismo del Fármaco, (IQUIMEFA) CONICET-Universidad de Buenos Aires; Cátedra de Farmacognosia, Facultad de Farmacia y Bioquímica, Universidad de Buenos Aires, C1113AAD Buenos Aires, Argentina.ORCID https://orcid.org/0000-0002-9322-5748

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In the ongoing search for effective antiviral agents against dengue virus (DENV), we have isolated a promising compound from a relatively unexplored natural source. This study describes the isolation, structural elucidation, and biological evaluation of a carboxylated sesquiterpene lactone, desacyl grazielia acid tiglate, from

Identifiers

PMID41141737
PMCPMC12547525

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.