ArticleFood science & nutrition2025
A Novel Dietary Index for Gut Microbiota (DI-GM) is Associated With Inflammation, Mental Health, and Tumor Biomarkers in Adults: A Cross-Sectional Study.
Article in Food science & nutrition, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
3 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Gut Microbiota Modulation as a Therapeutic Strategy for Insomnia: A Systematic Review of Nutritional and Botanical Interventions.Biomolecules · 2026Pooled it
- Dietary index for gut microbiota and risk of incident gastroesophageal reflux disease: a prospective cohort analysis integrating plasma proteomics in the UK Biobank.Frontiers in nutrition · 2026Article
- A Novel Dietary Index for Gut Microbiota (DI-GM) is Associated With Inflammation, Mental Health, and Tumor Biomarkers in Adults: A Cross-Sectional Study.Food science & nutrition · 2025Article
Corrections and comments
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The interplay between diet, gut microbiota, and mental health has garnered increasing attention. This study aimed to examine the association of a novel Dietary Index for Gut Microbiota (DI-GM) with depression, anxiety, and intestinal tumor biomarkers, and to explore whether gut microbiota composition mediates these associations. A cross-sectional study was conducted among 650 Chinese adults aged 18-65 years. DI-GM scores were calculated based on habitual dietary intake. Mental health was assessed using PHQ-9, STAI-A, PSQI, and WHO-5. Gut microbiota metrics (Firmicutes/Bacteroidetes [F/B] ratio, alpha diversity), inflammatory markers (CRP, calprotectin, TMAO), brain-derived neurotrophic factor (BDNF), and carcinoembryonic antigen (CEA) were measured. Linear regression and structural equation modeling were used to assess associations and mediation effects. Higher DI-GM scores were significantly associated with lower BMI, improved lipid profiles (↑ HDL-C:
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.