ArticleFrontiers in veterinary science2025
Effect of vitamin D3 supplementation on thyroid function of clinically healthy dogs.
Article in Frontiers in veterinary science, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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4 authors.
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Abstract
Introduction: Vitamin D has diverse effects on different organ functions. This study evaluated the effect of vitamin D3 supplementation on thyroid function of healthy dogs by repeated assays of thyroid hormones (including total and free T4 and T3) as well as TSH levels during a 6 week-period. Methods: Eight healthy adult male dogs received vitamin D3 supplements at the dose of 50 IU/kg BW per day. Venous blood samples were collected on days 0, 14, 28 and 42 of the experiment. Results: Six-week vitamin D3 supplementation statistically increased serum T4 levels [ Discussion: Vitamin D3 supplementation to healthy dogs is associated with a time-dependent change in thyroid hormone profile (increased serum T4 and fT4) which are probably mediated at the thyroid gland level as shown by the negative feedback on serum TSH concentrations. These findings pave the road for future studies on the plausible effects of this vitamin on thyroid function of hypothyroid dogs.
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