Evidence map›Paper›PMID 41144229›Full record

ArticleBone & joint research2025

Genotype and phenotype correlation analysis in 27 families with multiple osteochondroma and validation by ATDC5 chondrocyte models.

Xiaoyan Guo, Mingrui Lin, Shan Xu, Boling Liu, Rui Zhang, Shu Liu, Yuancheng Pan

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Bone & joint research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Xiaoyan GuoDepartment of Laboratory Medicine, Fuzhou Second General Hospital, Fuzhou, China.
Mingrui LinDepartment of Intensive Care Unit, the People's Hospital of Fujian Traditional Medical University, Fuzhou, China.
Shan XuBiomedical Research Center of South China, Fujian Normal University, Fuzhou, China.
Boling LiuDepartment of Orthopedics, Fuzhou Second General Hospital, Fuzhou, China.
Rui ZhangDepartment of Laboratory Medicine, Fuzhou Second General Hospital, Fuzhou, China.
Shu LiuDepartment of Laboratory Medicine, Fuzhou Second General Hospital, Fuzhou, China.
Yuancheng PanDepartment of Orthopedics, Fuzhou Second General Hospital, Fuzhou, China.

Funding

Natural Science Foundation of Fujian ProvinceScience and Technology Bureau Project of Fuzhou
6 · The paper itself

Abstract

Aims: This study aimed to explore the genotype and phenotype correlation of patients with multiple osteochondroma (MO), and validate phenotypic differences in ATDC5 cell model with Methods: Mutation analysis was employed in 27 families with MO using polymerase chain reaction (PCR)-Sanger sequencing and targeted next-generation sequencing (t-NGS). ATDC5 cell model with Results: A total of 27 pathogenic mutations were identified in Conclusion: Clinical research identified nine novel mutations in

Identifiers

PMID41144229
PMCPMC12558417

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.