ArticleAdvanced science (Weinheim, Baden-Wurttemberg, Germany)2026
Marginal Stability of the YB1 Cold-Shock Domain in Cells Enables Binding of Multiple Nucleic Acids.
Article in Advanced science (Weinheim, Baden-Wurttemberg, Germany), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
1 citing paper in PubMed.
- Marginal Stability of the YB1 Cold-Shock Domain in Cells Enables Binding of Multiple Nucleic Acids.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Article
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Authors and funding
5 authors.
Funding
Abstract
YB1 is an intrinsically disordered protein with a folded cold shock domain (CSD) required for translation, transcription, and RNA metabolism. This multifunctionality and cancer involvement make it a therapeutically attractive target. YB1-CSD and nucleic acid interaction is essential for function. The CSD is marginally stable in vitro, with unknown implications for its function in the cell. In this study, the folding stability of the CSD in living cells is studied at the physiological levels of nucleic acids. The CSD is highly stabilized (increase in T
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Registered trials
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