Evidence map›Paper›PMID 41146027›Full record

ArticleEuropean review of aging and physical activity : official journal of the European Group for Research into Elderly and Physical Activity2025

Use it or lose it: a four-year follow-up assessing whether physical activity near one's capacity reduces the risk of functional decline among older adults.

Antti Löppönen, Katja Lindeman, Lotta Palmberg, Evelien Van Roie, Christophe Delecluse, Erja Portegijs, Taina Rantanen, Timo Rantalainen, Laura Karavirta

Abstract read
In one paragraph

Article in European review of aging and physical activity : official journal of the European Group for Research into Elderly and Physical Activity, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Antti LöppönenUniversity of Jyväskylä, Jyvaskyla, Finland. antti.ej.lopponen@jyu.fi.
Katja LindemanUniversity of Jyväskylä, Jyvaskyla, Finland.
Lotta PalmbergUniversity of Jyväskylä, Jyvaskyla, Finland.
Evelien Van RoieHasselt University, Hasselt, Belgium.
Christophe DelecluseKU Leuven, Leuven, Belgium.
Erja PortegijsUniversity of Groningen, Groningen, Netherlands.
Taina RantanenUniversity of Jyväskylä, Jyvaskyla, Finland.
Timo RantalainenUniversity of Jyväskylä, Jyvaskyla, Finland.
Laura KaravirtaUniversity of Jyväskylä, Jyvaskyla, Finland.

Funding

European Research Council 693045Research Council of Finland 310526Research Council of Finland 321336, 328818 and 352653Research Council of Finland 339391 and 346462
6 · The paper itself

Abstract

backgroundPhysical capacity (PC) defines the limits for physical activity (PA), while activities in daily life typically remain submaximal. Older adults whose daily activities approach their physical capacity may experience less functional decline, though prospective evidence is limited. This study compared changes in physical function over a four-year follow-up between community-dwelling older adults categorized based on their combined baseline physical capacity and physical activity.

methods312 community-dwelling older adults (75-85 years, 60% women) participated in this study. Baseline physical capacity was measured using the 5-second Mean Amplitude Deviation (MAD) during a maximal 10-meter walking test. Physical activity was assessed based on individuals' ~99.25th percentile MAD values from free-living accelerometry (representing an intensity equivalent to 75 min/week of physical activity), which were then used for group categorization into lowPC-lowPA, lowPC-highPA, highPC-lowPA, and highPC-highPA profiles. Physical function was assessed with the Short Physical Performance Battery (SPPB) and the 5x Sit-To-Stand (5xSTS) test. Analyses used nonparametric tests and generalized estimating equations.

resultsSignificant changes in SPPB and 5xSTS were observed in all profiles (p < 0.05) except for the lowPC-highPA profile. The decline in SPPB was greater for low versus high physical activity profiles in both PC profiles (high PC: B -0.61, SE 0.24, 95% CI -1.08, -0.15; low PC: B -0.96, SE 0.35, 95% CI -1.62, -0.32), but no significant difference was found for the decline in 5xSTS time between physical activity profiles in either physical capacity profile.

conclusionsEngaging in physically demanding activities, irrespective of baseline physical capacity, may help slow functional decline in old age. Older adults should be encouraged to engage in physically demanding activities to enhance their functional capacity.

Indexed as

Device-basedFree-living activitiesMobility limitationWalking test

Identifiers

PMID41146027
PMCPMC12560511

What Socratic holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.