Evidence map›Paper›PMID 41147014›Full record

ArticleAsia-Pacific journal of sports medicine, arthroscopy, rehabilitation and technology2025

Quantitative assessment of graft maturation after anterior cruciate ligament reconstruction using quadriceps tendon: Insights from ultra short echo time T2∗ mapping.

Naoki Takemoto, Yasushi Takata, Miho Okuda, Yoshihiro Ishida, Manase Nishimura, Kentaro Fujita, Mikino Saito, Satoru Demura, Junsuke Nakase

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Article in Asia-Pacific journal of sports medicine, arthroscopy, rehabilitation and technology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Naoki TakemotoDepartment of Orthopaedic Surgery, Graduate School of Medical Sciences, Kanazawa University, 13-1, Takaramachi, Kanazawa, Ishikawa, 920-8641, Japan.
Yasushi TakataDepartment of Orthopaedic Surgery, Graduate School of Medical Sciences, Kanazawa University, 13-1, Takaramachi, Kanazawa, Ishikawa, 920-8641, Japan.
Miho OkudaDepartment of Radiology, Kanazawa University Hospital, 13-1, Takaramachi, Kanazawa, Ishikawa, 920-8641, Japan.
Yoshihiro IshidaDepartment of Orthopedic Surgery, KKR Hokuriku Hospital, 2-13-43, Izumigaoka, Kanazawa, Ishikawa, 921-8035, Japan.
Manase NishimuraDepartment of Orthopaedic Surgery, Graduate School of Medical Sciences, Kanazawa University, 13-1, Takaramachi, Kanazawa, Ishikawa, 920-8641, Japan.
Kentaro FujitaDepartment of Orthopaedic Surgery, Graduate School of Medical Sciences, Kanazawa University, 13-1, Takaramachi, Kanazawa, Ishikawa, 920-8641, Japan.
Mikino SaitoDepartment of Orthopaedic Surgery, Graduate School of Medical Sciences, Kanazawa University, 13-1, Takaramachi, Kanazawa, Ishikawa, 920-8641, Japan.
Satoru DemuraDepartment of Orthopaedic Surgery, Graduate School of Medical Sciences, Kanazawa University, 13-1, Takaramachi, Kanazawa, Ishikawa, 920-8641, Japan.
Junsuke NakaseDepartment of Orthopaedic Surgery, Graduate School of Medical Sciences, Kanazawa University, 13-1, Takaramachi, Kanazawa, Ishikawa, 920-8641, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Recently, the quadriceps tendon (QT) has gained attention as a graft material for anterior cruciate ligament (ACL) reconstruction. However, no study has yet evaluated the maturation process of the reconstructed ACL using QT grafts. Magnetic resonance imaging (MRI)-Ultra Short Echo time (UTE) T2∗ mapping is a precise technique for quantifying tissue states in tendons and ligaments. This study aimed to prospectively observe trends in UTE-T2∗ values for the intra-articular and intra-osseous regions of the reconstructed ACL from 6 to 12 months following ACL reconstruction using MRI-UTE-T2∗ mapping and to assess graft maturation of the reconstructed ACL with QT grafts. Methods: This study enrolled 10 patients (five males and five females). For each patient, UTE-T2∗ values were measured at 6, 9, and 12 months postoperatively. A two-way mixed ANOVA was performed with time (6, 9, and 12 months) as a within-subjects factor and location (intra-articular, tibial intra-osseous, and femoral intra-osseous) as a between-subjects factor. Results: A significant main effect of time was observed (F (2,54) = 38.162, p < 0.001), with UTE-T2∗ values decreasing as postoperative time progressed. Additionally, a significant main effect of measurement location was identified (F (2,27) = 95.853, p < 0.001), with intra-articular UTE-T2∗ values being significantly higher than those in the tibial and femoral intra-osseous regions (p < 0.001). Conclusion: Quantitative assessment using MRI-UTE-T2∗ mapping following ACL reconstruction with QT grafts demonstrated that graft maturation progressed more rapidly in the intra-osseous region compared to the intra-articular region.

Indexed as

Anterior cruciate ligament reconstructionMagnetic resonance imagingQuadriceps tendonReturn to sportsUltra short echo time T2∗ mapping

Identifiers

PMID41147014
PMCPMC12554058

What Socratic holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.