Evidence map›Paper›PMID 41147735›Full record

ArticlePest management science2026

Unlocking the genetic control of early seedling resistance to wheat powdery mildew through microphenomics.

Amira M I Mourad, Hanaa M S Ibrahim, Stefanie Lück, Andreas Börner, Dimitar Douchkov

Abstract read
In one paragraph

Article in Pest management science, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Amira M I MouradLeibniz Institute of Plant Genetics and Crop Plant Research (IPK), Seeland, Germany.ORCID https://orcid.org/0000-0001-6879-2559
Hanaa M S IbrahimLeibniz Institute of Plant Genetics and Crop Plant Research (IPK), Seeland, Germany.
Stefanie LückLeibniz Institute of Plant Genetics and Crop Plant Research (IPK), Seeland, Germany.ORCID https://orcid.org/0000-0003-0536-835X
Andreas BörnerLeibniz Institute of Plant Genetics and Crop Plant Research (IPK), Seeland, Germany.ORCID https://orcid.org/0000-0003-3301-9026
Dimitar DouchkovLeibniz Institute of Plant Genetics and Crop Plant Research (IPK), Seeland, Germany.ORCID https://orcid.org/0000-0001-6603-4930

Funding

Alexander von Humboldt-StiftungGerman Federal Ministry of Education and Research (BMBF)
6 · The paper itself

Abstract

backgroundPowdery mildew is one of the most devastating diseases affecting wheat-growing areas worldwide. The most effective strategy for managing this disease is through the cultivation of resistant genotypes.

resultsIn this study, early resistance was assessed in a set of 197 spring wheat genotypes using a novel Microphenomics approach. Parameters measured using this technique were: the number of micro-colonies 48 h post-infection (N48), the median colony area 72 h post-infection (M72), and the area under the disease progress curve (AUDPC). No significant correlations were found among these parameters. Single-locus and multi-locus GWAS revealed 57, 61, and 57 significant markers associated with N48, M72, and AUDPC, respectively. These markers were located within 29, 42, and 34 genes, respectively. Gene enrichment analysis uncovered 17 biological processes (BP), 13 cellular components, and one molecular function pathway. The 17 BP pathways formed a single network controlled by five gene models. Eight genotypes were identified as highly resistant based on all evaluation parameters.

conclusionMicrophenomics is a cutting-edge technique that facilitates large-scale quantification of the early, often critical stages of plant-pathogen interactions, providing unprecedented insights into the infection process and enabling the discovery of new resistance mechanisms. SL and ML-GWAS, along with gene enrichment analysis, provided a deeper understanding of the genetic control of WPM early resistance. Genotypes from Oman and the UK were particularly notable as good sources for improving early resistance to wheat powdery mildew due to their superior response and the high genetic distance between them and the German genotypes. © 2025 The Author(s). Pest Management Science published by John Wiley & Sons Ltd on behalf of Society of Chemical Industry.

Indexed as

AscomycotaDisease ResistancePlant DiseasesSeedlingsTriticumGenome-Wide Association StudyGenotypeBluVisiongene enrichmentgenetic distancemultilocus genome‐wide association studyselectionsingle locus genome‐wide association study

Identifiers

PMID41147735
PMCPMC12790651

What Socratic holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.