Evidence map›Paper›PMID 41148128›Full record

ArticleScience progress

Clinical characteristics and outcomes of Chlamydia psittaci pneumonia: Insights from targeted next-generation sequencing diagnosis.

Zhixiong He, Xuelian Chen, Ruixiang Chu, Yaman Luo, Xiaowen He, Yuling Tang

Abstract read
In one paragraph

Article in Science progress. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

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4 · The record

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PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Zhixiong HeDepartment of Respiratory and Critical Care Medicine, The First Hospital of Changsha (The Affiliated Changsha Hospital of Xiangya School of Medicine, Central South University), Changsha, China.ORCID 0009-0004-8477-2338
Xuelian ChenDepartment of Respiratory and Critical Care Medicine, The First Hospital of Changsha (The Affiliated Changsha Hospital of Xiangya School of Medicine, Central South University), Changsha, China.
Ruixiang ChuDepartment of Respiratory and Critical Care Medicine, The First Hospital of Changsha (The Affiliated Changsha Hospital of Xiangya School of Medicine, Central South University), Changsha, China.ORCID 0009-0009-6536-9929
Yaman LuoThe Affiliated Changsha Hospital of Xiangya School of Medicine, Central South University, Changsha, China.
Xiaowen HeThe Affiliated Changsha Hospital of Xiangya School of Medicine, Central South University, Changsha, China.ORCID 0009-0008-5205-9676
Yuling TangDepartment of Respiratory and Critical Care Medicine, The First Hospital of Changsha (The Affiliated Changsha Hospital of Xiangya School of Medicine, Central South University), Changsha, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

ObjectiveThe aim is to enhance clinician awareness of the disease, reduce the risk of misdiagnosis, and analyze the risk factors for the progression of Chlamydia psittaci infection to severe pneumonia.MethodsWe conducted a retrospective analysis of the clinical data from patients infected with Chlamydia psittaci at our hospital.ResultsThirty-three patients diagnosed with Chlamydia psittaci pneumonia were included in this study. Among them, 23 (72.2%) were male and 10 (27.8%) were female, with a mean age of 59.1 ± 11.1 years. Twenty-four patients (72.7%) had a clear history of poultry exposure. The main clinical manifestations were high fever (n = 30, 90.9%), cough (n = 28, 84.8%), chill (n = 24, 72.7%), expectoration (n = 22, 66.7%), fatigue (n = 20, 60.6%), poor appetite (n = 20, 60.6%), dyspnea (n = 13, 39.4%), and myalgia (n = 10, 30.3%). The lymphocyte count in severe pneumonia group was significantly lower than that in non-severe pneumonia group. C-reactive protein, erythrocyte sedimentation rate, and lactate dehydrogenase levels in the severe group were remarkably higher than those in the non-severe group. The common imaging findings included flake high-density shadows (n = 29, 87.9%), consolidation (n = 20, 60.6%), pleural effusion (n = 17, 51.5%), bronchial inflation signs (n = 15, 45.5%), and ground-glass exudation (n = 20, 60.6%). The majority of patients received treatment with either doxycycline alone, quinolones alone, or a combination of doxycycline and quinolones.ConclusionHistory of contact with birds or poultry, repeated high fever, and flake high-density shadows with consolidation in Chest computed tomography can serve as important indicators for diagnosing C. psittaci pneumonia. Lower lymphocyte counts were identified as the sole risk factor associated with severe C. psittaci pneumonia. Quinolones and doxycycline are effective treatments for C. psittaci pneumonia.

Indexed as

Chlamydophila psittaciHigh-Throughput Nucleotide SequencingPsittacosisAdultAgedAnti-Bacterial AgentsDoxycyclineFemaleHumansMaleMiddle AgedRetrospective StudiesAnti-Bacterial AgentsDoxycyclineChlamydia psittaciclinical characteristicsdoxycyclinepneumoniaquinolonetargeted next-generation sequencing (tNGS)

Identifiers

PMID41148128
PMCPMC12576283

What Socratic holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.