Evidence mapPaperPMID 41148858Full record

ArticleCells2025

Vascular Endothelial Growth Factor B Modulates Cardiac Functions via Ferroptosis Pathways in Post-Myocardial Infarction.

Sai Manasa Varanasi, Ankit Sabharwal, Shreyartha Mukherjee, Huzaifa Muhammad, Riya Kar, Carter Magnano, Anya Dorairaj, Enfeng Wang, Shamit Dutta, Pritam Das and 4 more

Abstract read
In one paragraph

Article in Cells, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Hyperoxia and iron homeostasis in developing human airway smooth muscle.American journal of physiology. Lung cellular and molecular physiology · 2026
    Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Sai Manasa VaranasiDepartment of Biochemistry and Molecular Biology, Mayo Clinic College of Medicine and Sciences, Jacksonville, FL 32224, USA.ORCID 0009-0003-4259-5604
Ankit SabharwalDepartment of Biochemistry and Molecular Biology, Mayo Clinic College of Medicine and Science, Rochester, MN 55905, USA.
Shreyartha MukherjeeDepartment of Quantitative Health Sciences, Mayo Clinic, Jacksonville, FL 32224, USA.ORCID 0009-0003-9896-0746
Huzaifa MuhammadDepartment of Biochemistry and Molecular Biology, Mayo Clinic College of Medicine and Sciences, Jacksonville, FL 32224, USA.
Riya KarDepartment of Biochemistry and Molecular Biology, Mayo Clinic College of Medicine and Sciences, Jacksonville, FL 32224, USA.
Carter MagnanoDepartment of Biochemistry and Molecular Biology, Mayo Clinic College of Medicine and Sciences, Jacksonville, FL 32224, USA.
Anya DorairajDepartment of Biochemistry and Molecular Biology, Mayo Clinic College of Medicine and Sciences, Jacksonville, FL 32224, USA.
Enfeng WangDepartment of Biochemistry and Molecular Biology, Mayo Clinic College of Medicine and Sciences, Jacksonville, FL 32224, USA.
Shamit DuttaDepartment of Biochemistry and Molecular Biology, Mayo Clinic College of Medicine and Sciences, Jacksonville, FL 32224, USA.
Pritam DasDepartment of Biochemistry and Molecular Biology, Mayo Clinic College of Medicine and Sciences, Jacksonville, FL 32224, USA.
Stephen C EkkerDepartment of Biochemistry and Molecular Biology, Mayo Clinic College of Medicine and Science, Rochester, MN 55905, USA.
Ying WangDepartment of Biochemistry and Molecular Biology, Mayo Clinic College of Medicine and Sciences, Jacksonville, FL 32224, USA.
Debabrata MukhopadhyayDepartment of Biochemistry and Molecular Biology, Mayo Clinic College of Medicine and Sciences, Jacksonville, FL 32224, USA.ORCID 0000-0003-1858-5054
Ramcharan Singh AngomDepartment of Biochemistry and Molecular Biology, Mayo Clinic College of Medicine and Sciences, Jacksonville, FL 32224, USA.ORCID 0000-0002-5894-1108

Funding

Systematic Vertebrate Functional GenomicsR01GM063904 · UNIVERSITY OF TEXAS AT AUSTIN · 2001 to 2025
$3.3M
Distinct Pathways of VPF/VEGF ReceptorsR01HL140411 · MAYO CLINIC JACKSONVILLE · 2025 to 2025
$653k
Florida Department of Health DeSantis grant 91803004,MUG22 DeSantis grant 91925093NHLBI NIH HHS R01 HL140411NIGMS NIH HHS R01 GM063904NIH HHS 2R01HL140411-05A1
6 · The paper itself

Abstract

Myocardial infarction (MI) remains a leading cause of mortality worldwide, yet effective cardioprotective strategies remain limited in clinical settings.

Indexed as

FerroptosisMyocardial InfarctionVascular Endothelial Growth Factor BAnimalsDisease Models, AnimalHumansMyocytes, CardiacNeuropilin-1Reactive Oxygen SpeciesSignal TransductionZebrafishNeuropilin-1Reactive Oxygen SpeciesVascular Endothelial Growth Factor BcardiomyocytesFerroptosishypoxia/ischemiamitochondrial dysfunctionmyocardial infarctionNeuropilin-1 (NRP1)vascular endothelial growth factor B (VEGFB)zebrafish

Identifiers

PMID41148858
PMCPMC12562414

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.