Evidence map›Paper›PMID 41148869›Full record

ReviewInsects2025

Ecological Mercenaries: Why Aphids Remain Premier Models for the Study of Ecological Symbiosis.

Roy A Kucuk, Benjamin R Trendle, Kenedie C Jones, Alina Makarenko, Vilas Patel, Kerry M Oliver

Abstract readReview
In one paragraph

Review in Insects, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Roy A KucukDepartment of Entomology, University of Georgia, Athens, GA 30602, USA.
Benjamin R TrendleDepartment of Entomology, University of Georgia, Athens, GA 30602, USA.
Kenedie C JonesDepartment of Entomology, University of Georgia, Athens, GA 30602, USA.
Alina MakarenkoDepartment of Entomology, University of Georgia, Athens, GA 30602, USA.
Vilas PatelDepartment of Entomology, University of Georgia, Athens, GA 30602, USA.
Kerry M OliverDepartment of Entomology, University of Georgia, Athens, GA 30602, USA.

Funding

U.S. National Science Foundation 2240392
6 · The paper itself

Abstract

Aphids remain exceptional models for symbiosis research due to their unique experimental advantages that extend beyond documenting symbiont-mediated phenotypes. Nine commonly occurring facultative bacterial symbionts provide well-characterized benefits, including defense against parasitoids, pathogens, and thermal stress. Yet the system's greatest value lies in enabling diverse research applications across biological disciplines through experimental tractability combined with ecological realism. Researchers can create controlled experimental lines through symbiont manipulation, maintain clonal host populations indefinitely, and cultivate symbionts independently. This experimental power is complemented by extensive knowledge of symbiont dynamics in natural populations, including temporal and geographic distribution patterns-features generally unavailable in other insect-microbe systems. These advantages facilitate investigation of key processes in symbiosis, including transmission dynamics, mechanisms, strain-level functional diversity, multi-partner infections, and transitions from facultative to co-obligate relationships. Integration across biological scales-from genomics to field ecology-enables research on symbiont community assembly, ecological networks, coevolutionary arms races, and agricultural applications. This combination of experimental flexibility, comprehensive natural history knowledge, and applied relevance positions aphids as invaluable for advancing symbiosis theory while addressing practical challenges in agriculture and invasion biology.

Indexed as

biological controlclimate changecoevolutiondefensive mutualismfacultative symbiontsHamiltonella defensaheritable symbiontshost–microbehost–parasitoidinsect pathogens

Identifiers

PMID41148869
PMCPMC12563771

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.