Evidence map›Paper›PMID 41149709›Full record

ArticleJournal of functional biomaterials2025

Magnesium Ion-Mediated Regulation of Osteogenesis and Osteoclastogenesis in 2D Culture and 3D Collagen/Nano-Hydroxyapatite Scaffolds for Enhanced Bone Repair.

Sílvia Sá Paiva, Avelino Ferreira, Eavan Pakenham, Kulwinder Kaur, Brenton Cavanagh, Fergal J O'Brien, Ciara M Murphy

Abstract read
In one paragraph

Article in Journal of functional biomaterials, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Sílvia Sá PaivaTissue Engineering Research Group (TERG), Department of Anatomy & Regenerative Medicine, RCSI University of Medicine and Health Sciences, D02 YN77 Dublin, Ireland.ORCID 0009-0008-4687-0841
Avelino FerreiraTissue Engineering Research Group (TERG), Department of Anatomy & Regenerative Medicine, RCSI University of Medicine and Health Sciences, D02 YN77 Dublin, Ireland.
Eavan PakenhamTissue Engineering Research Group (TERG), Department of Anatomy & Regenerative Medicine, RCSI University of Medicine and Health Sciences, D02 YN77 Dublin, Ireland.
Kulwinder KaurTissue Engineering Research Group (TERG), Department of Anatomy & Regenerative Medicine, RCSI University of Medicine and Health Sciences, D02 YN77 Dublin, Ireland.ORCID 0000-0001-5352-0542
Brenton CavanaghCellular and Molecular Imaging Core, RCSI University of Medicine and Health Sciences, D02 YN77 Dublin, Ireland.ORCID 0000-0002-1582-5756
Fergal J O'BrienTissue Engineering Research Group (TERG), Department of Anatomy & Regenerative Medicine, RCSI University of Medicine and Health Sciences, D02 YN77 Dublin, Ireland.ORCID 0000-0003-2030-8005
Ciara M MurphyTissue Engineering Research Group (TERG), Department of Anatomy & Regenerative Medicine, RCSI University of Medicine and Health Sciences, D02 YN77 Dublin, Ireland.ORCID 0000-0002-9653-5477

Funding

Advanced Materials and BioEngineering Research 17/RC-PhD/3477Anatomical Society 22516A01European Research Council GAP-101125820 (RESTORE)Taighde Éireann - Research Ireland 17/RC-PhD/3477
6 · The paper itself

Abstract

Bone regeneration depends on a delicate balance between osteoblast-driven bone formation and osteoclast-mediated resorption, coordinated by complex biochemical cues. Magnesium (Mg

Indexed as

bone regenerationcollagen–nanohydroxyapatite scaffoldsmagnesiumosteoclastogenesisosteogenesis

Identifiers

PMID41149709
PMCPMC12565561

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.