Evidence map›Paper›PMID 41152187›Full record

ArticleAlzheimer's & dementia : the journal of the Alzheimer's Association2025

Higher vitamin B

Francesca R Marino, Gail Rogers, Joshua W Miller, Jacob Selhub, Jesse Mez, Paul K Crane, Shubhabrata Mukherjee, Andrew J Saykin, Timothy J Hohman, Emily H Trittschuh and 3 more

Abstract read
In one paragraph

Article in Alzheimer's & dementia : the journal of the Alzheimer's Association, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Higher vitamin BAlzheimer's & dementia : the journal of the Alzheimer's Association · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Francesca R MarinoDepartment of Anatomy and Neurobiology, Boston University Chobanian and Avedisian School of Medicine, Boston, Massachusetts, USA.ORCID 0000-0001-9641-052X
Gail RogersThe Framingham Heart Study, Boston University Chobanian and Avedisian School of Medicine, Boston, Massachusetts, USA.
Joshua W MillerDepartment of Nutritional Sciences, Rutgers University, New Brunswick, New Jersey, USA.
Jacob SelhubUSDA Human Nutrition Research Center on Aging, Tufts University, Boston, Massachusetts, USA.
Jesse MezThe Framingham Heart Study, Boston University Chobanian and Avedisian School of Medicine, Boston, Massachusetts, USA.
Paul K CraneDivision of General Internal Medicine, University of Washington School of Medicine, Seattle, Washington, USA.
Shubhabrata MukherjeeDivision of General Internal Medicine, University of Washington School of Medicine, Seattle, Washington, USA.
Andrew J SaykinDepartment of Radiology and Imaging Sciences, Indiana University School of Medicine, Indianapolis, Indiana, USA.
Timothy J HohmanVanderbilt Memory and Alzheimer's Center, Vanderbilt University Medical Center, Nashville, Tennessee, USA.
Emily H TrittschuhDepartment of Psychiatry and Behavioral Sciences, University of Washington School of Medicine, Seattle, Washington, USA.
Rhoda AuDepartment of Anatomy and Neurobiology, Boston University Chobanian and Avedisian School of Medicine, Boston, Massachusetts, USA.
Paul F JacquesUSDA Human Nutrition Research Center on Aging, Tufts University, Boston, Massachusetts, USA.
Phillip H HwangDepartment of Anatomy and Neurobiology, Boston University Chobanian and Avedisian School of Medicine, Boston, Massachusetts, USA.

Funding

MVP Data Integration into the ADSP Phenotype Harmonization ConsortiumU24AG074855 · NIA · VANDERBILT UNIVERSITY MEDICAL CENTER · PI CUCCARO, MICHAEL L, HOHMAN, TIMOTHY J · 2021 to 2025
$37.5M
University of Washington Alzheimer's Disease Research CenterP30AG066509 · NIA · UNIVERSITY OF WASHINGTON · PI Caitlin Shannon Latimer · 2020 to 2026
$29.0M
NHLBI TRANS-OMICS FOR PRECISION MEDICINE (TOPMED) FOR THE CENTRALIZED OMICS RESOURCE (CORE) - TASK AREAS 2, 3, AND 4 - 2024 TASK ORDER75N92023D00012 · NHLBI · BAYLOR COLLEGE OF MEDICINE · PI OSBORNE, C KENT · 2023 to 2025
$27.9M
Ultrascale Machine Learning to Empower Discovery in Alzheimers Disease BiobanksU01AG068057 · NIA · UNIVERSITY OF SOUTHERN CALIFORNIA · PI Christos Davatzikos, Heng Huang · 2020 to 2026
$20.7M
FRAMINGHAM HEART STUDY (FHS), TASK AREA B - PROTOCOL DEVELOPMENT AND BASIC EXAMINATION75N92025D00012 · NHLBI · BOSTON UNIVERSITY (CHARLES RIVER CAMPUS) · PI LLOYD-JONES, DONALD · 2025 to 2025
$8.9M
Leveraging Existing Aging Research Networks to investigate TBI and AD/ADRD risk (LEARN TBI & AD)R01AG061028 · NIA · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI DAMS-O'CONNOR, KRISTEN, MEZ, JESSE BENJAMIN · 2019 to 2023
$5.9M
Genetic Drivers of Resilience to Alzheimer's DiseaseR01AG059716 · NIA · VANDERBILT UNIVERSITY MEDICAL CENTER · PI HOHMAN, TIMOTHY J · 2018 to 2022
$4.4M
CLC NIH HHS HHSN269201500001CCLC NIH HHS HHSN269201500001INHLBI NIH HHS 75N92023D00012NHLBI NIH HHS 75N92025D00012NHLBI NIH HHS HHSN269201500001INHLBI NIH HHS N01-HC-25195NIA NIH HHS P30 AG066509NIA NIH HHS R01 AG059716NIA NIH HHS R01AG059716NIA NIH HHS R01 AG061028NIA NIH HHS U01 AG068057NIA NIH HHS U01AG068057NIA NIH HHS U24 AG074855NIA NIH HHS U24AG074855NIH HHS 75N98025D00012
6 · The paper itself

Abstract

introductionEvidence is needed to evaluate whether low vitamin B

methodsParticipants from the Framingham Heart Study without baseline dementia who had ≥ 2 measures of a three-component vitamin B

resultsParticipants in the highest 3cB DISCUSSION: Improving B HIGHLIGHTS: Higher vitamin B

Indexed as

Cognitive DysfunctionVitamin B 12AgedExecutive FunctionFemaleFolic AcidHumansMaleMiddle AgedNeuropsychological TestsFolic AcidVitamin B 12cognitive declinedementialifestylenutritionprevention

Identifiers

PMID41152187
PMCPMC12568389

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.