Observational studyAnnals of medicine2025
Vascular characteristics and haemodynamics of severe and mild pterygium: a quantitative analysis.
Observational study in Annals of medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
2 citing papers in PubMed.
- Proteomic and Clinical Characterization of Active vs. Quiescent Pterygium With Elevated Thrombospondin-1.Translational vision science & technology · 2026Article
- Complement C5a Promotes Epithelial-Mesenchymal Transition in Pterygium via C5aR Activation.Investigative ophthalmology & visual science · 2026Article
Corrections and comments
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Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeTo investigate vascular characteristics and hemodynamic changes in mild and severe pterygium and explore correlations among clinical parameters.
designCross-sectional observational study.
methodsSixty-three patients (68 eyes) with pterygium, classified into mild (32 eyes) and severe (36 eyes) groups, and 30 healthy controls (36 eyes) were included. Pterygium length and area were measured via slit-lamp photography. Optical coherence tomography angiography assessed pterygium thickness and vessel density. A functional slit-lamp biomicroscopy measured vessel diameter, vessel length and blood flow velocities. Correlation analysis was performed for each parameter.
resultsThe vessel density was significantly higher in the pterygium groups compared to the control group (
conclusionsPterygium demonstrates elevated ocular surface vascular density that correlates with disease severity. Changes in vascular morphology include vessel dilation and increased branching, with dilation most prominent in mild pterygium and branching in severe pterygium. These findings enhance the understanding of pterygium progression and may inform severity-based clinical management.
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Registered trials
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