Trial reportScientific reports2025
A randomized trial on the feasibility of high-intensity interval training during chemotherapy in young breast cancer patients.
Trial report in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06190600 (Supervised Physical Activity in Young Women With Early Breast Cancer During Neoadjuvant Chemotherpy), which is not on this map. Not yet cited in PubMed.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Supervised Physical Activity in Young Women With Early Breast Cancer During Neoadjuvant Chemotherpy
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
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Authors and funding
15 authors.
Funding
Abstract
Chemotherapy used to treat breast cancer (BC) in young women often results in significant side effects, among others myelotoxicity, nausea, neurotoxicity, ataxia, and fatigue. These negative effects can be offset by physical activity employed concurrently with the treatment. One of the training modalities - high-intensity interval training (HIIT) - has been the subject of many studies showing significant health benefits, with the advantage of being time-efficient. The aim of this study was to investigate whether HIIT can be successfully employed for young BC patients undergoing chemotherapy. Forty young (18-40 years old) BC patients scheduled for chemotherapy were randomized to undergo supervised HIIT concurrently with chemotherapy or instructed to perform World Health Organization-recommended volume of daily physical activity (control group). Measurements included retention, adherence to training, and body composition parameters (BMI, muscle mass, fat mass, handgrip strength on affected and unaffected side) measured before and after therapy. HIIT scheduled concurrently with chemotherapy was a feasible approach for young BC patients (retention: 94.74%, adherence: 100%). Employment of HIIT also resulted in higher handgrip strength compared to no supervised training (1.2 kg between-group difference). This study shows that HIIT introduced and conducted along the chemotherapy is feasible for young BC patients. This approach can offset the negative effects of chemotherapy on physical fitness.Trial registrationThe study was registered in the clinicaltrials.gov registry (#NCT06190600) on 05/01/2024, retrospectively registered.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.