ArticleScientific reports2025
Olfactory gene dynamics in invasive Indian and non-invasive African malaria vectors at the crossroads of development, infection and resistance.
Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- GravidInsects · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Olfaction plays a pivotal role in a mosquito's lifecycle, influencing vital functions such as finding food, mates, identifying hosts, and locating sites for laying eggs. However, a detailed catalog of the olfactory genes in mosquitoes has remained elusive-until now. In this study, we compiled the olfactory genes catalog for four key malaria vectors: two major Indian species, Anopheles stephensi and Anopheles culicifacies, along with two African species, Anopheles gambiae and Anopheles funestus. Using an extensive genome-wide approach, we uncovered crucial carrier proteins like odorant binding proteins (OBPs), chemosensory proteins (CSPs), and several receptors, including odorant receptors (ORs), ionotropic receptors (IRs), and gustatory receptors (GusRs). A particularly striking discovery was the significantly higher number of OBP, OR, and IR genes in African malaria vectors compared to their Indian counterparts, hinting at the gene gain and functional diversification in these species. The invasive A. stephensi-which has spread from Asia to Africa-showed closer genetic ties to A. minimus and A. gambiae than to A. culicifacies. Furthermore, when examining the expression of CSPs and SAPs in the larval stage of A. stephensi, we found that pyrethroid-resistant mosquito larvae exhibited elevated expression of SAP2 and SAP3, providing new evidence of their potential role in insecticide resistance. This study not only sheds light on the genetic basis of mosquito olfaction but also offers crucial insights into how these genes are linked to different physiological functions, paving the way for improved malaria control strategies.
Indexed as
Identifiers
What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.