Evidence map›Paper›PMID 41153022›Full record

ReviewStem cell research & therapy2025

Mechanisms and applications of mesenchymal stem cell exosomes in enhancing fertility.

Yuhan Wang, Ruiling Wang, Yunxia Zhao, Nannan Han, Xiaojing Han, Tong Shi, Yamei Liu, Nian Zhao, Sufen Li, Shaoqiang Wang and 2 more

Abstract readReview
In one paragraph

Review in Stem cell research & therapy, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Review
  2. Review
  3. Review
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Yuhan WangWeifang People's Hospital, Shandong Second Medical University, Weifang, Shandong, 261000, China.
Ruiling WangWeifang People's Hospital, Shandong Second Medical University, Weifang, Shandong, 261000, China.
Yunxia ZhaoWeifang People's Hospital, Shandong Second Medical University, Weifang, Shandong, 261000, China.
Nannan HanWeifang People's Hospital, Shandong Second Medical University, Weifang, Shandong, 261000, China.
Xiaojing HanWeifang People's Hospital, Shandong Second Medical University, Weifang, Shandong, 261000, China.
Tong ShiWeifang People's Hospital, Shandong Second Medical University, Weifang, Shandong, 261000, China.
Yamei LiuWeifang People's Hospital, Shandong Second Medical University, Weifang, Shandong, 261000, China.
Nian ZhaoWeifang People's Hospital, Shandong Second Medical University, Weifang, Shandong, 261000, China.
Sufen LiWeifang People's Hospital, Shandong Second Medical University, Weifang, Shandong, 261000, China.
Shaoqiang Wang *Weifang People's Hospital, Shandong Second Medical University, Weifang, Shandong, 261000, China. rmyywsq227@sdsmu.edu.cn.
Niannian Li *Weifang People's Hospital, Shandong Second Medical University, Weifang, Shandong, 261000, China. liniannian123liu@163.com.
Yuchun Zhu *Weifang People's Hospital, Shandong Second Medical University, Weifang, Shandong, 261000, China. zyc15065658122@163.com.ORCID http://orcid.org/0009-0003-5296-0097

Funding

National Natural Science Foundation of China 32261160571National Natural Science Foundation of China 82230052
6 · The paper itself

Abstract

Infertility is an increasingly prevalent global health issue affecting millions of couples. It can arise from various factors, including hormonal imbalances, reproductive disorders, and anatomical abnormalities. While numerous treatment options exist, such as assisted reproductive technologies, these approaches often entail significant costs and have limited success rates. In this paper, we review the role of mesenchymal stem cell exosomes (MSC-Exos) in the treatment of infertility, with a particular focus on their potential to enhance fertility. We herein aimed to integrate the latest research progress in this field and emphasize the importance of MSC-Exos as a potential treatment for infertility.

Indexed as

ExosomesFertilityInfertilityMesenchymal Stem CellsAnimalsFemaleHumansMaleMesenchymal Stem Cell TransplantationFertility treatmentInfertilityMesenchymal stem cell-derived exosomesTherapeutics

Identifiers

PMID41153022
PMCPMC12570428

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.