ArticleBiomedicines2025
FAD012, a Ferulic Acid Derivative, Preserves Cerebral Blood Flow and Blood-Brain Barrier Integrity in the Rat Photothrombotic Stroke Model.
Hiroshi Sugoh, Hirokazu Matsuzaki, Jun Takayama, Naohiro Iwata, Meiyan Xuan, Bo Yuan, Takeshi Sakamoto, Mari Okazaki
Abstract read
In one paragraphArticle in Biomedicines, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
2 · The registryThe trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
3 · Its place in the literatureWho cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
4 · The recordCorrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
5 · Who and what moneyAuthors and funding
8 authors.
Hiroshi SugohLaboratory of Pharmacology, Graduate School of Pharmaceutical Sciences, Josai University, Saitama 350-0295, Japan.
Hirokazu MatsuzakiLaboratory of Pharmacology, Graduate School of Pharmaceutical Sciences, Josai University, Saitama 350-0295, Japan.ORCID 0009-0002-0592-5160 Jun TakayamaLaboratory of Organic and Medicinal Chemistry, Graduate School of Pharmaceutical Sciences, Josai University, Saitama 350-0295, Japan.
Naohiro IwataLaboratory of Immunobiochemistry, Graduate School of Pharmaceutical Sciences, Josai University; Saitama 350-0295, Japan.
Meiyan XuanLaboratory of Organic and Medicinal Chemistry, Graduate School of Pharmaceutical Sciences, Josai University, Saitama 350-0295, Japan.
Bo YuanLaboratory of Pharmacology, Graduate School of Pharmaceutical Sciences, Josai University, Saitama 350-0295, Japan.ORCID 0000-0002-3406-258X Takeshi SakamotoLaboratory of Organic and Medicinal Chemistry, Graduate School of Pharmaceutical Sciences, Josai University, Saitama 350-0295, Japan.
Mari OkazakiLaboratory of Pharmacology, Graduate School of Pharmaceutical Sciences, Josai University, Saitama 350-0295, Japan.ORCID 0000-0001-6452-6907 Funding
Grants-in-Aid for Scientific Research from the Japan Society for the Promotion of Science 25460910, 16K09255, 19K07873
6 · The paper itselfAbstract
PubMed holds no abstract for this paper.
Indexed as
3,5-dimethyl-4-hydroxycinnamic acid (ferulic acid derivative 012blood–brain barrier (BBB)brain infarctioncerebral blood flow (CBF)cerebral vascular endothelial cellsendothelial nitric oxide synthase (eNOS)FAD012)ferulic acid (FA)photothrombotic stroketight junction (TJ) protein
Identifiers
PMID41153685
PMCPMC12561687
What Socratic holds
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LicenceCC BY
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