Evidence map›Paper›PMID 41153827›Full record

ArticleBiomedicines2025

Short-Term Cyclosporin A Treatment Reduced Serum Neurofilament-Light Levels in Diffuse but Not Focal Traumatic Brain Injury in a Piglet Model.

Colin M Huber, Akshara D Thakore, Anna Oeur, Susan S Margulies

Abstract read
In one paragraph

Article in Biomedicines, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Colin M HuberWallace H. Coulter Department of Biomedical Engineering, Georgia Institute of Technology and Emory University, Atlanta, GA 30332, USA.ORCID 0000-0002-0045-5940
Akshara D ThakoreWallace H. Coulter Department of Biomedical Engineering, Georgia Institute of Technology and Emory University, Atlanta, GA 30332, USA.ORCID 0000-0002-3106-0159
Anna OeurWallace H. Coulter Department of Biomedical Engineering, Georgia Institute of Technology and Emory University, Atlanta, GA 30332, USA.ORCID 0000-0002-5587-3517
Susan S MarguliesWallace H. Coulter Department of Biomedical Engineering, Georgia Institute of Technology and Emory University, Atlanta, GA 30332, USA.ORCID 0000-0002-3615-7902

Funding

Biomechanics of Pediatric Head InjuryR01NS039679 · NINDS · UNIVERSITY OF PENNSYLVANIA · PI MARGULIES, SUSAN SHEPS · 2001 to 2011
$5.0M
Objective Translational Multi-domain Early Concussion AssessmentR01NS097549 · NINDS · UNIVERSITY OF PENNSYLVANIA · PI ARBOGAST, KRISTY, MARGULIES, SUSAN SHEPS · 2017 to 2021
$4.5M
PRECLINICAL CYCLOSPORIN A THERAPY TRIALS FOR PEDIATRIC TBIU01NS069545 · NINDS · UNIVERSITY OF PENNSYLVANIA · PI DUHAIME, ANN-CHRISTINE, MARGULIES, SUSAN SHEPS · 2011 to 2017
$3.5M
NIH HHS 1R01NS039679-15NIH HHS 1R01NS097549-17NIH HHS 1U01NS069545-11NINDS NIH HHS R01 NS039679NINDS NIH HHS R01 NS097549NINDS NIH HHS U01 NS069545
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

cyclosporin Apediatricserum biomarkersswinetraumatic brain injury

Identifiers

PMID41153827
PMCPMC12561874

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.