Evidence map›Paper›PMID 41154591›Full record

ArticleBiomolecules2025

The Respiratory Burst of Human Granulocytes Is Mostly Independent of Potassium.

Iryna Mahorivska, Martin Geltinger, Gustavo Chaves, Sebastian Lobmann, Martin Jakab, Katharina Helm, Boris Musset

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Biomolecules, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Iryna MahorivskaCenter of Physiology, Pathophysiology and Biophysics, Paracelsus Medical University, 90419 Nuremberg, Germany.
Martin GeltingerCenter of Physiology, Pathophysiology and Biophysics, Paracelsus Medical University, 90419 Nuremberg, Germany.
Gustavo ChavesCenter of Physiology, Pathophysiology and Biophysics, Paracelsus Medical University, 90419 Nuremberg, Germany.ORCID 0000-0003-2599-8885
Sebastian LobmannCenter of Physiology, Pathophysiology and Biophysics, Paracelsus Medical University, 90419 Nuremberg, Germany.
Martin JakabCenter of Physiology, Pathophysiology and Biophysics, Paracelsus Medical University, 5020 Salzburg, Austria.ORCID 0000-0003-2110-5090
Katharina HelmCenter of Physiology, Pathophysiology and Biophysics, Paracelsus Medical University, 5020 Salzburg, Austria.ORCID 0000-0002-4436-1946
Boris MussetCenter of Physiology, Pathophysiology and Biophysics, Paracelsus Medical University, 90419 Nuremberg, Germany.ORCID 0000-0001-8242-8817

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Reactive oxygen species (ROS) are among the most effective tools of the innate immune response against pathogenic microbes. The respiratory burst (RB) of polymorphonuclear leukocytes (PMNs) generates an electron current that reduces molecular oxygen to superoxide. Superoxide reacts to form hydrogen peroxide as a precursor to the highly bactericidal hypochlorous acid. Here, we investigated whether alterations in extracellular potassium concentration impact H

Indexed as

GranulocytesPotassiumRespiratory BurstHumansHydrogen PeroxideNeutrophilsReactive Oxygen SpeciesSuperoxidesHydrogen PeroxidePotassiumReactive Oxygen SpeciesSuperoxidesleucocytesNADPH oxidaseosmolalitypotassiumrespiratory burstvoltage-gated proton channel

Identifiers

PMID41154591
PMCPMC12564300

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.