Evidence map›Paper›PMID 41154675›Full record

ArticleBiomolecules2025

Bacterial Lysates Modulate Human Macrophage Responses by Inducing BPI Production and Autophagy.

Yael García-González, María Teresa Herrera, Esmeralda Juárez, Teresa Santos-Mendoza, Yolanda González, Eduardo Becerril-Vargas, Silvia Guzmán-Beltrán

Abstract read
In one paragraph

Article in Biomolecules, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Editorial comment: Efficacy and safety of bacterial immunostimulants in immunodeficient individuals: A systematic review and meta-analysis.Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology · 2026
    Article
  2. PulmonaromFrontiers in cellular and infection microbiology · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Yael García-GonzálezDepartamento de Investigación en Microbiología, Instituto Nacional de Enfermedades Respiratorias Ismael Cosío Villegas, Calzada de Tlalpan 4502, Sección XVI, Alcaldía de Tlalpan, Mexico City 14080, Mexico.ORCID 0009-0009-7192-794X
María Teresa HerreraDepartamento de Investigación en Microbiología, Instituto Nacional de Enfermedades Respiratorias Ismael Cosío Villegas, Calzada de Tlalpan 4502, Sección XVI, Alcaldía de Tlalpan, Mexico City 14080, Mexico.ORCID 0000-0001-7941-5468
Esmeralda JuárezLaboratorio de Alta Contención Biológica (LACBio), Instituto Nacional de Enfermedades Respiratorias Ismael Cosío Villegas, Calzada de Tlalpan 4502, Sección XVI, Alcaldía de Tlalpan, Mexico City 14080, Mexico.ORCID 0000-0001-9036-004X
Teresa Santos-MendozaLaboratorio de Transcriptómica e Inmunología Molecular, Instituto Nacional de Enfermedades Respiratorias Ismael, Cosío Villegas, Calzada de Tlalpan 4502, Sección XVI, Alcaldía de Tlalpan, Mexico City 14080, Mexico.ORCID 0000-0003-1015-5631
Yolanda GonzálezDepartamento de Investigación en Microbiología, Instituto Nacional de Enfermedades Respiratorias Ismael Cosío Villegas, Calzada de Tlalpan 4502, Sección XVI, Alcaldía de Tlalpan, Mexico City 14080, Mexico.ORCID 0000-0002-7066-6188
Eduardo Becerril-VargasLaboratorio de Microbiología Clínica, Instituto Nacional de Enfermedades Respiratorias Ismael Cosío Villegas, Calzada de Tlalpan 4502, Sección XVI, Alcaldía de Tlalpan, Mexico City 14080, Mexico.ORCID 0000-0003-1339-3942
Silvia Guzmán-BeltránDepartamento de Investigación en Microbiología, Instituto Nacional de Enfermedades Respiratorias Ismael Cosío Villegas, Calzada de Tlalpan 4502, Sección XVI, Alcaldía de Tlalpan, Mexico City 14080, Mexico.ORCID 0000-0002-7491-1910

Funding

Instituto Nacional de Enfermedades Respiratorias Ismael Cosío VIllegas B12-23
6 · The paper itself

Abstract

Bacterial lysates have emerged as promising immunomodulatory agents that can enhance innate immune responses. Given the crucial role of macrophages in recognizing and controlling intracellular pathogens such as

Indexed as

Antimicrobial Cationic PeptidesAutophagyBlood ProteinsMacrophagesBacterial LysatesCytokinesHumansMycobacterium tuberculosisAntimicrobial Cationic PeptidesBacterial Lysatesbactericidal permeability increasing proteinBlood ProteinsCytokinesautophagybacterial lysatesbactericidal/permeability-increasing proteinMycobacterium tuberculosis

Identifiers

PMID41154675
PMCPMC12562339

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.