Evidence map›Paper›PMID 41154694›Full record

ArticleBiomolecules2025

PAX6 Downregulation Triggers HIF-1α-Mediated Ferroptosis in Glioma Cells.

Qizhi Luo, Li Fu, Jie Zhang, Shashuang Zhang, Lixiang Wu, Quan Zhu, Baisheng Huang

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Biomolecules, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Qizhi LuoExperimental Center for Cellular and Molecular Biology, School of Basic Medical Sciences, Central South University, Changsha 410017, China.
Li FuDepartment of Immunology, School of Basic Medical Sciences, Central South University, Changsha 410017, China.
Jie ZhangExperimental Center for Cellular and Molecular Biology, School of Basic Medical Sciences, Central South University, Changsha 410017, China.
Shashuang ZhangExperimental Center for Cellular and Molecular Biology, School of Basic Medical Sciences, Central South University, Changsha 410017, China.
Lixiang WuDepartment of Physiology, School of Basic Medical Sciences, Central South University, Changsha 410017, China.
Quan ZhuDepartment of Immunology, Medical College, Hunan University of Chinese Medicine, Changsha 410208, China.
Baisheng HuangTop-Notch Innovation Base of Basic Medicine, Central South University, Changsha 410017, China.

Funding

Natural Science Foundation of Hunan Province 2019JJ40398Natural Science Foundation of Hunan Province 2020JJ4768
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Brain NeoplasmsFerroptosisGliomaHypoxia-Inducible Factor 1, alpha SubunitPAX6 Transcription FactorCell Line, TumorDown-RegulationGene Expression Regulation, NeoplasticHumansPhospholipid Hydroperoxide Glutathione PeroxidaseReactive Oxygen SpeciesHIF1A protein, humanHypoxia-Inducible Factor 1, alpha SubunitPAX6 protein, humanPAX6 Transcription FactorPhospholipid Hydroperoxide Glutathione PeroxidaseReactive Oxygen SpeciesferroptosisgliomaHIF-1αPAX6

Identifiers

PMID41154694
PMCPMC12564151

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.