Evidence map›Paper›PMID 41155237›Full record

ArticleInternational journal of molecular sciences2025

Rhythmic Dynamics of Stress Granules in

Melisa Malcolm, Julio M Pusterla, Laura G Penazzi, Alejandra Trenchi, Victoria A Acosta-Rodríguez, Maximiliano N Ríos, Marcos Villarreal, Mario E Guido, Eduardo Garbarino-Pico

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Melisa MalcolmDepartamento de Química Biológica Ranwel Caputto, Facultad de Ciencias Químicas, Universidad Nacional de Córdoba, Cordoba X5000HUA, Argentina.
Julio M PusterlaDepartamento de Química Biológica Ranwel Caputto, Facultad de Ciencias Químicas, Universidad Nacional de Córdoba, Cordoba X5000HUA, Argentina.ORCID 0000-0002-2996-5290
Laura G PenazziDepartamento de Química Biológica Ranwel Caputto, Facultad de Ciencias Químicas, Universidad Nacional de Córdoba, Cordoba X5000HUA, Argentina.
Alejandra TrenchiInstituto Multidisciplinario de Biología Vegetal (IMBIV), CONICET, Universidad Nacional de Córdoba, Cordoba X5000HUA, Argentina.
Victoria A Acosta-RodríguezDepartamento de Química Biológica Ranwel Caputto, Facultad de Ciencias Químicas, Universidad Nacional de Córdoba, Cordoba X5000HUA, Argentina.ORCID 0000-0002-4818-0667
Maximiliano N RíosDepartamento de Química Biológica Ranwel Caputto, Facultad de Ciencias Químicas, Universidad Nacional de Córdoba, Cordoba X5000HUA, Argentina.ORCID 0000-0003-3692-6553
Marcos VillarrealInstituto de Investigaciones en Físico-Química de Córdoba (INFIQC-CONICET), Departamento de Química Teórica y Computacional, Facultad de Ciencias Químicas, Universidad Nacional de Córdoba, Cordoba X500HUA, Argentina.
Mario E GuidoDepartamento de Química Biológica Ranwel Caputto, Facultad de Ciencias Químicas, Universidad Nacional de Córdoba, Cordoba X5000HUA, Argentina.ORCID 0000-0002-5485-4904
Eduardo Garbarino-PicoDepartamento de Química Biológica Ranwel Caputto, Facultad de Ciencias Químicas, Universidad Nacional de Córdoba, Cordoba X5000HUA, Argentina.ORCID 0000-0002-2931-2038

Funding

Agencia Nacional de Promoción de la Investigación, el Desarrollo Tecnológico y la Innovación PICT 2020-0613Consejo Nacional de Investigaciones Científicas y Técnicas PIP 2020Universidad Nacional de Córdoba Consolidar 2023Universidad Nacional de Córdoba Formar 2023
6 · The paper itself

Abstract

Circadian rhythms are endogenous ~24 h oscillations that regulate diverse biochemical processes. Although stress responses can exhibit circadian modulation, evidence for rhythmic regulation of stress granules (SGs)-cytoplasmic RNA-protein condensates formed under stress-remains limited. We investigated sodium arsenite-induced SG dynamics in NIH/3T3 cultures. SG number, eIF3 signal intensity-an established SG marker-and area oscillated with a period of ~24 h. These rhythms persisted in

Indexed as

ARNTL Transcription FactorsCircadian ClocksCircadian RhythmFibroblastsStress GranulesAnimalsMiceMice, KnockoutNIH 3T3 CellsPhosphorylationARNTL Transcription FactorsBmal1 protein, mousebiocondensatesbiological clockBMAL1circadian rhythmsfibroblastsstress granulesstress responsetranscription–translation feedback loop (TTFL)

Identifiers

PMID41155237
PMCPMC12564134

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.