Evidence map›Paper›PMID 41155303›Full record

ArticleInternational journal of molecular sciences2025

Vaping in Pregnancy: Unraveling Molecular Drivers of Preeclampsia and Fetal Growth Restriction.

Archarlie Chou, Olivia Hiatt, Benjamin Davidson, Paul R Reynolds, Brett E Pickett, Juan A Arroyo

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Archarlie ChouDepartment of Microbiology and Molecular Biology, Brigham Young University, Provo, UT 84602, USA.
Olivia HiattDepartment of Cell Biology and Physiology, Brigham Young University, 3052 LSB, Provo, UT 84602, USA.
Benjamin DavidsonDepartment of Cell Biology and Physiology, Brigham Young University, 3052 LSB, Provo, UT 84602, USA.
Paul R ReynoldsDepartment of Cell Biology and Physiology, Brigham Young University, 3052 LSB, Provo, UT 84602, USA.ORCID 0000-0002-0931-3025
Brett E PickettDepartment of Microbiology and Molecular Biology, Brigham Young University, Provo, UT 84602, USA.ORCID 0000-0001-7930-8160
Juan A ArroyoDepartment of Cell Biology and Physiology, Brigham Young University, 3052 LSB, Provo, UT 84602, USA.ORCID 0000-0002-8818-8786

Funding

RAGE targeting attenuates smoke-induced inflammationR15HL152257 · NHLBI · BRIGHAM YOUNG UNIVERSITY · PI REYNOLDS, PAUL R · 2020 to 2025
$879k
Receptor for advanced glycation end-products signaling induction in the lung and placenta due to secondhand smoke and e-cigarette vaporR15HD108743 · NICHD · BRIGHAM YOUNG UNIVERSITY · PI ARROYO, JUAN A · 2022 to 2022
$455k
NHLBI NIH HHS R15 HL152257NICHD NIH HHS R15 HD108743NIH HHS 1R15HD108743-01NIH HHS 2R15HL152257-02
6 · The paper itself

Abstract

Preeclampsia (PE) and intrauterine growth restriction (IUGR) are major pregnancy complications that are linked to placental dysfunction and environmental stimulation such as the use of electronic cigarettes (eCig). This study investigates the molecular impacts of timed eCig exposure in a C57BL/6 mouse model of PE and IUGR using bulk RNA-sequencing of placental tissues. Pregnant mice were exposed to eCig vapor via nose-only system starting at embryonic day 12.5 (eCig-6d, before spiral artery (SA) invasion) or 14.5 (eCig-4d, after SA invasion) until E18.5 (necropsy), with healthy controls exposed to room air (

Indexed as

Fetal Growth RetardationPre-EclampsiaVapingAnimalsDisease Models, AnimalFemaleGene Regulatory NetworksMiceMice, Inbred C57BLPlacentaPregnancyelectronic cigaretteintrauterine growth restrictionplacental dysfunctionpreeclampsiaRNA-sequencing

Identifiers

PMID41155303
PMCPMC12562910

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.