Evidence map›Paper›PMID 41155453›Full record

ArticleInternational journal of molecular sciences2025

Berberine Alleviates Intestinal Inflammation by Disrupting Pathological Macrophage-Epithelial Crosstalk in Macrophage-Organoid Co-Culture Model.

Yuncong Han, Mengting Li, Tian Chen, Chen Wang, Hong Zhou, Tunan Zhou, Runqing Jia, Ying Chen, Qin Hu

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of molecular sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Review
  2. Review
  3. Review
  4. Berberine AlleviatesInternational journal of molecular sciences · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Yuncong HanCollege of Chemistry and Life Science, Beijing University of Technology, Beijing 100124, China.
Mengting LiInstitute of Chinese Materia Medica, China Academy of Chinese Medical Sciences, Beijing 100700, China.
Tian ChenCollege of Chemistry and Life Science, Beijing University of Technology, Beijing 100124, China.
Chen WangCollege of Chemistry and Life Science, Beijing University of Technology, Beijing 100124, China.
Hong ZhouCollege of Chemistry and Life Science, Beijing University of Technology, Beijing 100124, China.
Tunan ZhouCollege of Chemistry and Life Science, Beijing University of Technology, Beijing 100124, China.
Runqing JiaCollege of Chemistry and Life Science, Beijing University of Technology, Beijing 100124, China.
Ying ChenInstitute of Chinese Materia Medica, China Academy of Chinese Medical Sciences, Beijing 100700, China.
Qin HuCollege of Chemistry and Life Science, Beijing University of Technology, Beijing 100124, China.ORCID 0000-0003-1196-879X

Funding

Major Science and Technology Project in the Autonomous Region 2023A02010-3the Fundamental Research Funds for the Central public welfare research institutes ZXKT25004the National Key Research and Development Program of China 2023YFF0724803the National Natural Science Foundation of China 82074103
6 · The paper itself

Abstract

Berberine (BBR), a benzylisoquinoline alkaloid isolated from Chinese herb

Indexed as

Anti-Inflammatory AgentsBerberineEpithelial CellsInflammationIntestinal MucosaMacrophagesOrganoidsAnimalsCell CommunicationCoculture TechniquesInflammatory Bowel DiseasesLipopolysaccharidesMiceMice, Inbred C57BLRAW 264.7 CellsAnti-Inflammatory AgentsBerberineLipopolysaccharidesanti-inflammationberberineco-culture modelintestinal organoid

Identifiers

PMID41155453
PMCPMC12563409

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.