Evidence map›Paper›PMID 41155994›Full record

ArticlePharmaceutics2025

Design, Synthesis and Biological Evaluation of Pyrazolopyrimidine Derivatives as Aryl Hydrocarbon Receptor Antagonists for Colorectal Cancer Immunotherapy.

Byeong Wook Choi, Jae-Eon Lee, Da Bin Jeon, Pyeongkeun Kim, Gwi Bin Lee, Saravanan Parameswaran, Ji Yun Jang, Gopalakrishnan Chandrasekaran, So Yeon Jeong, Geumi Park and 13 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Pharmaceutics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

23 authors.

Byeong Wook ChoiDepartment of Chemistry, Gwangju Institute of Science and Technology, Gwangju 61005, Republic of Korea.ORCID 0000-0003-1989-131X
Jae-Eon LeePreclinical Research Center, Daegu-Gyeongbuk Medical Innovation Foundation (K-MEDIhub), Daegu 41061, Republic of Korea.
Da Bin JeonDepartment of Biomedical Sciences, Chonnam National University Medical School, Hwasun 58128, Republic of Korea.
Pyeongkeun KimDepartment of Chemistry, Gwangju Institute of Science and Technology, Gwangju 61005, Republic of Korea.ORCID 0009-0004-1203-2533
Gwi Bin LeeDepartment of Chemistry, Gwangju Institute of Science and Technology, Gwangju 61005, Republic of Korea.
Saravanan ParameswaranDepartment of Biotechnology and Bioinformatics, School of Life Sciences, JSS Academy of Higher Education and Research, Mysuru 570015, India.ORCID 0000-0001-9279-2620
Ji Yun JangDepartment of Biomedical Sciences, Chonnam National University Medical School, Hwasun 58128, Republic of Korea.
Gopalakrishnan ChandrasekaranDepartment of Biomedical Sciences, Chonnam National University Medical School, Hwasun 58128, Republic of Korea.
So Yeon JeongPreclinical Research Center, Daegu-Gyeongbuk Medical Innovation Foundation (K-MEDIhub), Daegu 41061, Republic of Korea.
Geumi ParkPreclinical Research Center, Daegu-Gyeongbuk Medical Innovation Foundation (K-MEDIhub), Daegu 41061, Republic of Korea.
Kyoung-Jin MinNew Drug Development Center, Daegu-Gyeongbuk Medical Innovation Foundation (K-MEDIhub), Daegu 41061, Republic of Korea.
Heegyum MoonNew Drug Development Center, Daegu-Gyeongbuk Medical Innovation Foundation (K-MEDIhub), Daegu 41061, Republic of Korea.
Jihyeon YoonDepartment of Chemistry, Gwangju Institute of Science and Technology, Gwangju 61005, Republic of Korea.ORCID 0000-0001-8923-9197
Yerim HeoDepartment of Chemistry, Gwangju Institute of Science and Technology, Gwangju 61005, Republic of Korea.
Donggun KimDepartment of Chemistry, Gwangju Institute of Science and Technology, Gwangju 61005, Republic of Korea.
Se Hwan AhnDepartment of Chemistry, Gwangju Institute of Science and Technology, Gwangju 61005, Republic of Korea.
You Jeong ChoiDepartment of Chemistry, Gwangju Institute of Science and Technology, Gwangju 61005, Republic of Korea.
Seong Soon KimTherapeutics & Biotechnology Division, Korea Research Institute of Chemical Technology (KRICT), Daejeon 34114, Republic of Korea.ORCID 0000-0002-4762-8693
Jung Yoon YangTherapeutics & Biotechnology Division, Korea Research Institute of Chemical Technology (KRICT), Daejeon 34114, Republic of Korea.
Myung Ae BaeTherapeutics & Biotechnology Division, Korea Research Institute of Chemical Technology (KRICT), Daejeon 34114, Republic of Korea.
Yong Hyun JeonPreclinical Research Center, Daegu-Gyeongbuk Medical Innovation Foundation (K-MEDIhub), Daegu 41061, Republic of Korea.
Seok-Yong ChoiDepartment of Biomedical Sciences, Chonnam National University Medical School, Hwasun 58128, Republic of Korea.ORCID 0000-0001-7193-292X
Jin Hee AhnDepartment of Chemistry, Gwangju Institute of Science and Technology, Gwangju 61005, Republic of Korea.ORCID 0000-0002-6957-6062

Funding

Korea Environmental Industry and Technology Institute RS-2020-KE000885Ministry of Health & Welfare HI22C1988National Research Foundation of Korea 2022R1A2C1004096National Research Foundation of Korea RS-2024-00348338National Research Foundation of Korea RS-2024-00411137
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

antagonistaryl hydrocarbon receptorcancerzebrafish

Identifiers

PMID41155994
PMCPMC12567141

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.