Evidence map›Paper›PMID 41156397›Full record

ArticleMicromachines2025

Nanostructured Scaffold, Combined with Human Dental Pulp Stem Cell Secretome, Induces Vascularization in Medicinal Leech Model.

Gaia Marcolli, Nicolò Baranzini, Ludovica Barone, Federica Rossi, Laura Pulze, Christina Pagiatakis, Roberto Papait, Annalisa Grimaldi, Rosalba Gornati

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Micromachines, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Gaia MarcolliDepartment of Biotechnology and Life Sciences, University of Insubria, 21100 Varese, Italy.
Nicolò BaranziniDepartment of Biotechnology and Life Sciences, University of Insubria, 21100 Varese, Italy.ORCID 0000-0001-6996-4797
Ludovica BaroneDepartment of Biotechnology and Life Sciences, University of Insubria, 21100 Varese, Italy.ORCID 0000-0002-8553-222X
Federica RossiDepartment of Biotechnology and Life Sciences, University of Insubria, 21100 Varese, Italy.ORCID 0000-0001-5983-3646
Laura PulzeDepartment of Biotechnology and Life Sciences, University of Insubria, 21100 Varese, Italy.
Christina PagiatakisDepartment of Biotechnology and Life Sciences, University of Insubria, 21100 Varese, Italy.ORCID 0000-0002-9315-9648
Roberto PapaitDepartment of Biotechnology and Life Sciences, University of Insubria, 21100 Varese, Italy.
Annalisa GrimaldiDepartment of Biotechnology and Life Sciences, University of Insubria, 21100 Varese, Italy.ORCID 0000-0002-9258-7595
Rosalba GornatiDepartment of Biotechnology and Life Sciences, University of Insubria, 21100 Varese, Italy.ORCID 0000-0002-1544-2122

Funding

University of Insubria, Italy FAR_2025
6 · The paper itself

Abstract

As life expectancy continues to increase, age-related disorders are becoming more prevalent. Among these, vascular complications resulting from chronic inflammation are particularly concerning, as they impair angiogenesis and hinder tissue repair, both processes that heavily rely on a well-structured extracellular matrix (ECM). In this context, MicroMatrix

Indexed as

cell-free devicehuman Dental Pulp Stem Cellsmedicinal leechnanostructured scaffoldsecretometissue regeneration

Identifiers

PMID41156397
PMCPMC12565914

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.