Evidence map›Paper›PMID 41156439›Full record

ReviewNutrients2025

The Role of Nutritional Therapy in the Treatment of Adults with Crohn's Disease: A Review.

Raffaele Li Voti, Fabio Salvatore Macaluso, Elena Banci, Angelo Campanozzi, Giulia D'Arcangelo, Alessia De Blasi, Salvatore Oliva, Elena Sofia Pieri, Sara Renzo, Cosimo Ruggiero and 4 more

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Nutrients, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Raffaele Li VotiInflammatory Bowel Disease Unit, "Villa Sofia-Cervello" Hospital, 90146 Palermo, Italy.
Fabio Salvatore MacalusoInflammatory Bowel Disease Unit, "Villa Sofia-Cervello" Hospital, 90146 Palermo, Italy.ORCID 0000-0001-5128-3846
Elena BanciDietetics Unit, Meyer Children's Hospital IRCCS, 50139 Florence, Italy.
Angelo CampanozziPediatrics, Department of Medical and Surgical Sciences, University of Foggia, 71100 Foggia, Italy.ORCID 0000-0002-3489-2524
Giulia D'ArcangeloPediatrics, Department of Medical and Surgical Sciences, University of Foggia, 71100 Foggia, Italy.
Alessia De BlasiGastroenterology and Nutrition Unit, Meyer Children's Hospital IRCCS, 50139 Florence, Italy.
Salvatore OlivaPediatric Gastroenterology and Liver Unit, Maternal and Child Health Department, Sapienza University of Rome, 00185 Rome, Italy.
Elena Sofia PieriPediatrics, Department of Medical and Surgical Sciences, University of Foggia, 71100 Foggia, Italy.
Sara RenzoGastroenterology and Nutrition Unit, Meyer Children's Hospital IRCCS, 50139 Florence, Italy.ORCID 0009-0007-6094-7983
Cosimo RuggieroPediatric Gastroenterology and Liver Unit, Maternal and Child Health Department, Sapienza University of Rome, 00185 Rome, Italy.
Giusy RussoPediatric Gastroenterology and Liver Unit, Maternal and Child Health Department, Sapienza University of Rome, 00185 Rome, Italy.
Luca ScaralloGastroenterology and Nutrition Unit, Meyer Children's Hospital IRCCS, 50139 Florence, Italy.ORCID 0000-0003-1056-4400
Paolo LionettiGastroenterology and Nutrition Unit, Meyer Children's Hospital IRCCS, 50139 Florence, Italy.
Ambrogio OrlandoInflammatory Bowel Disease Unit, "Villa Sofia-Cervello" Hospital, 90146 Palermo, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Crohn's disease (CD) is an immune-mediated inflammatory bowel disease (IBD) with a multifactorial pathogenesis involving genetic predisposition, immune dysregulation, and environmental triggers. Dietary patterns have recently garnered growing attention for their potential benefits and risks in patients with IBD. Nutritional therapy has been established as an effective option in pediatric populations, but its role in adults remains less defined. The available studies indicate that while no single diet can be universally recommended, adherence to a Mediterranean diet is associated with multiple health benefits. Nutritional therapy appears promising in inducing clinical remission in adults with mild to moderate CD, particularly when partial enteral nutrition is combined with food-based modifications. Tailoring these strategies to cultural contexts and providing support from qualified dietitians may improve adherence, clinical outcomes, and overall quality of life. This review highlights the growing role of nutritional therapy in adult CD and its potential integration into routine management alongside conventional treatments.

Indexed as

Crohn DiseaseNutrition TherapyAdultDiet, MediterraneanEnteral NutritionHumansQuality of LifeTreatment OutcomeadultsCrohn’s diseaseCrohn’s disease exclusion dietMediterranean dietnutritional therapy

Identifiers

PMID41156439
PMCPMC12567425

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.