Evidence mapPaperPMID 41156530Full record

ReviewNutrients2025

Hepatoprotective Effect of Silymarin Herb in Prevention of Liver Dysfunction Using Pig as Animal Model.

Prarthana Sharma, Varun Asediya, Garima Kalra, Sharmin Sultana, Nihal Purohit, Kamila Kibitlewska, Wojciech Kozera, Urszula Czarnik, Krzysztof Karpiesiuk, Marek Lecewicz and 20 more

Abstract readReview
In one paragraph

Review in Nutrients, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Total Flavonoids fromInternational journal of molecular sciences · 2026
    Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

30 authors.

Prarthana SharmaDepartment of Pig Breeding, Faculty of Animal BioEngineering, University of Warmia and Mazury in Olsztyn, 10-719 Olsztyn, Poland.ORCID 0000-0002-1906-9767
Varun AsediyaInstitute of Veterinary Medicine, Department of Infectious, Invasive Diseases and Veterinary Administration, Faculty of Biological and Veterinary Sciences, Nicolaus Copernicus University, 87-100 Toruń, Poland.ORCID 0000-0002-9402-0349
Garima KalraInstitute of Veterinary Medicine, Department of Infectious, Invasive Diseases and Veterinary Administration, Faculty of Biological and Veterinary Sciences, Nicolaus Copernicus University, 87-100 Toruń, Poland.ORCID 0009-0003-1580-6373
Sharmin SultanaInstitute of Veterinary Medicine, Department of Infectious, Invasive Diseases and Veterinary Administration, Faculty of Biological and Veterinary Sciences, Nicolaus Copernicus University, 87-100 Toruń, Poland.ORCID 0009-0002-8792-5657
Nihal PurohitInstitute of Veterinary Medicine, Department of Infectious, Invasive Diseases and Veterinary Administration, Faculty of Biological and Veterinary Sciences, Nicolaus Copernicus University, 87-100 Toruń, Poland.ORCID 0009-0001-6762-4825
Kamila KibitlewskaDepartment of Pig Breeding, Faculty of Animal BioEngineering, University of Warmia and Mazury in Olsztyn, 10-719 Olsztyn, Poland.ORCID 0009-0007-8218-477X
Wojciech KozeraDepartment of Pig Breeding, Faculty of Animal BioEngineering, University of Warmia and Mazury in Olsztyn, 10-719 Olsztyn, Poland.ORCID 0000-0001-8931-3190
Urszula CzarnikDepartment of Pig Breeding, Faculty of Animal BioEngineering, University of Warmia and Mazury in Olsztyn, 10-719 Olsztyn, Poland.ORCID 0000-0002-9065-2197
Krzysztof KarpiesiukDepartment of Pig Breeding, Faculty of Animal BioEngineering, University of Warmia and Mazury in Olsztyn, 10-719 Olsztyn, Poland.ORCID 0000-0002-7334-5355
Marek LecewiczDepartment of Pig Breeding, Faculty of Animal BioEngineering, University of Warmia and Mazury in Olsztyn, 10-719 Olsztyn, Poland.ORCID 0000-0003-4062-3715
Paweł WysockiDepartment of Pig Breeding, Faculty of Animal BioEngineering, University of Warmia and Mazury in Olsztyn, 10-719 Olsztyn, Poland.ORCID 0000-0002-7018-3995
Adam LepczyńskiDepartment of Physiology, Cytobiology and Proteomics, Faculty of Biotechnology and Animal Husbandry, West Pomeranian University of Technology in Szczecin, 71-270 Szczecin, Poland.ORCID 0000-0002-5144-7940
Małgorzata OżgoDepartment of Physiology, Cytobiology and Proteomics, Faculty of Biotechnology and Animal Husbandry, West Pomeranian University of Technology in Szczecin, 71-270 Szczecin, Poland.ORCID 0000-0001-5558-2173
Marta MarynowskaDepartment of Physiology, Cytobiology and Proteomics, Faculty of Biotechnology and Animal Husbandry, West Pomeranian University of Technology in Szczecin, 71-270 Szczecin, Poland.
Agnieszka HerosimczykDepartment of Physiology, Cytobiology and Proteomics, Faculty of Biotechnology and Animal Husbandry, West Pomeranian University of Technology in Szczecin, 71-270 Szczecin, Poland.ORCID 0000-0001-7402-8266
Elżbieta RedlarskaDepartment of Physiology, Cytobiology and Proteomics, Faculty of Biotechnology and Animal Husbandry, West Pomeranian University of Technology in Szczecin, 71-270 Szczecin, Poland.ORCID 0000-0003-0140-8553
Brygida ŚlaskaInstitute of Biological Bases of Animal Production, Faculty of Animal Sciences and Bioeconomy, University of Life Sciences in Lublin, 20-950 Lublin, Poland.ORCID 0000-0003-3933-2400
Krzysztof KowalInstitute of Biological Bases of Animal Production, Faculty of Animal Sciences and Bioeconomy, University of Life Sciences in Lublin, 20-950 Lublin, Poland.ORCID 0000-0003-4716-5040
Angelika Tkaczyk-WlizłoInstitute of Biological Bases of Animal Production, Faculty of Animal Sciences and Bioeconomy, University of Life Sciences in Lublin, 20-950 Lublin, Poland.ORCID 0000-0003-2261-6909
Paweł GrychnikInstitute of Biological Bases of Animal Production, Faculty of Animal Sciences and Bioeconomy, University of Life Sciences in Lublin, 20-950 Lublin, Poland.ORCID 0009-0007-9770-7780
Athul P KurianInstitute of Biological Bases of Animal Production, Faculty of Animal Sciences and Bioeconomy, University of Life Sciences in Lublin, 20-950 Lublin, Poland.ORCID 0009-0000-0853-7361
Kaja Ziółkowska-TwarowskaInstitute of Biological Bases of Animal Production, Faculty of Animal Sciences and Bioeconomy, University of Life Sciences in Lublin, 20-950 Lublin, Poland.ORCID 0000-0001-6011-5043
Katarzyna ChałaśkiewiczDepartment of Genomics and Biodiversity, Institute of Genetics and Animal Biotechnology of the Polish Academy of Sciences, 05-552 Jastrzębiec, Poland.ORCID 0000-0003-3321-397X
Katarzyna Kępka-BorkowskaDepartment of Genomics and Biodiversity, Institute of Genetics and Animal Biotechnology of the Polish Academy of Sciences, 05-552 Jastrzębiec, Poland.ORCID 0000-0002-5801-4929
Ewa PoławskaDepartment of Genomics and Biodiversity, Institute of Genetics and Animal Biotechnology of the Polish Academy of Sciences, 05-552 Jastrzębiec, Poland.ORCID 0000-0002-6097-9826
Magdalena OgłuszkaDepartment of Genomics and Biodiversity, Institute of Genetics and Animal Biotechnology of the Polish Academy of Sciences, 05-552 Jastrzębiec, Poland.ORCID 0000-0001-6226-4114
Rafał R StarzyńskiDepartment of Genomics and Biodiversity, Institute of Genetics and Animal Biotechnology of the Polish Academy of Sciences, 05-552 Jastrzębiec, Poland.ORCID 0000-0002-7470-0507
Hiroaki TaniguchiDepartment of Genomics and Biodiversity, Institute of Genetics and Animal Biotechnology of the Polish Academy of Sciences, 05-552 Jastrzębiec, Poland.ORCID 0000-0001-7270-390X
Chandra Shekhar PareekInstitute of Veterinary Medicine, Department of Infectious, Invasive Diseases and Veterinary Administration, Faculty of Biological and Veterinary Sciences, Nicolaus Copernicus University, 87-100 Toruń, Poland.ORCID 0000-0002-0329-787X
Mariusz PierzchałaDepartment of Genomics and Biodiversity, Institute of Genetics and Animal Biotechnology of the Polish Academy of Sciences, 05-552 Jastrzębiec, Poland.ORCID 0000-0001-7001-1336

Funding

Deutsche Forschungsgemeinschaft 504983453National Science Centre UMO-2021/43/I/NZ9/02612
6 · The paper itself

Abstract

Silymarin, a flavonolignan-rich extract of

Indexed as

LiverLiver DiseasesPlant ExtractsProtective AgentsSilybum marianumSilymarinAnimalsDisease Models, AnimalOxidative StressSwinePlant ExtractsProtective AgentsSilymarinflavonolignanshepatoprotectioninflammationliver dysfunctionnutraceuticalsoxidative stresspharmacokineticspigs (Sus scrofa)silibininsilymarin

Identifiers

PMID41156530
PMCPMC12566644

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.