ReviewMedical review (2021)2025
Recent advances in understanding the relationship between lipid metabolism and immune escape in the tumor microenvironment of gastric cancer.
Review in Medical review (2021), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
3 citing papers in PubMed.
- Role of lipid-associated fibroblasts and their signature genes FABP4, CD36 and ABCA8 in gastric cancer progression.Oncology letters · 2026Article
- Fatty Acid Metabolism in Health and Cancer: From Fundamental Mechanisms to Therapeutic Application.MedComm · 2026Review
- New opportunities and challenges for nonshedder tumors.Fundamental research · 2026Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Gastric cancer (GC), a leading global malignancy, poses a significant threat to human health. Despite substantial therapeutic advances, drug resistance remains a major challenge for many patients. Aberrant lipid metabolism represents a hallmark in tumors; it critically contributes to GC pathogenesis. This review explores key enzymes and pathways driving lipid metabolic reprogramming within the GC immune microenvironment, which facilitates tumor immune evasion and chemotherapy resistance. This review also addresses the challenges posed by lipid metabolism reprogramming in clinical treatment, explores therapeutic perspectives and novel directions, and discusses metabolism-related mechanisms.
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What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.