Evidence map›Paper›PMID 41158296›Full record

ArticleFrontiers in allergy2025

Use of oral corticosteroids in patients with asthma: how far is clinical practice from the guidelines? Results from surveys of patients and doctors.

Luisa Brussino, Gianna Camiciottoli, Annalisa Stassaldi, Diego Bagnasco, Simona Barbaglia, Maria Beatrice Bilò, Cristiano Caruso, Filippo Cipriani, Renato Cutrera, Giuliana Nicolosi and 3 more

Abstract read
In one paragraph

Article in Frontiers in allergy, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Luisa Brussino *Dipartimento di Scienze Mediche, Università Degli Studi di Torino-SCDU Immunologia e Allergologia, AO Ordine Mauriziano di Torino, Turin, Italy.
Gianna Camiciottoli *Department of Clinical and Biomedical Sciences "Mario Serio", University of Florence-Severe Asthma Unit, Careggi University Hospital, Florence, Italy.
Annalisa StassaldiSanofi, Milan, Italy.
Diego BagnascoRespiratory and Allergy Clinic, IRCCS Ospedale Policlinico San Martino, Genoa, Italy.
Simona BarbagliaPresidente Associazione Nazionale Pazienti RESPIRIAMO INSIEME-APS, Padova, Italy.
Maria Beatrice BilòDepartment of Clinical and Molecular Science (DISCLIMO), Università Politecnica Delle Marche-Allergy Unit, Azienda Ospedaliero-Universitaria delle Marche, Ancona, Italy.
Cristiano CarusoUOSD Allergy and Clinical Immunology, Fondazione Policlinico A. Gemelli IRCCS, Rome, Italy.
Filippo CiprianiSanofi, Milan, Italy.
Renato CutreraPneumology and Cystic Fibrosis Unit, 'Bambino Gesù' Children's Hospital, IRCCS, Rome, Italy.
Giuliana NicolosiSanofi, Milan, Italy.
Jasmine NourSanofi, Milan, Italy.
Giulia SciosciaDepartment of Medical and Surgical Sciences, University of Foggia, Foggia, Italy.
Giorgio Walter CanonicaPersonalized Medicine, Asthma and Allergy, Humanitas Clinical and Research Center, IRCCS, Rozzano, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: Asthma is often treated with oral corticosteroids (OCS), despite their association with significant adverse effects. While guidelines recommend minimizing OCS use through alternative therapies and patient-centered approaches, discrepancies between recommendations and real-world practices persist. This study evaluates OCS usage patterns and barriers to adherence to asthma treatment guidelines in Italy, using surveys conducted with healthcare professionals (HCPs) and patients. Methods: Two cross-sectional surveys were administered between January and March 2024 to HCPs and asthma patients. The surveys assessed OCS prescription practices, treatment adherence, patient involvement, adverse event management, and perceptions of OCS use. Descriptive analysis was performed to identify patterns and highlight gaps in current practices. Results: The surveys revealed considerable variability in OCS prescribing practices, treatment duration and daily dosages. Over 80% of patients reported using OCS and 18% of HCPs believed that the maximum daily doses of OCS are higher than the guideline-recommended doses. Patients did not feel fully involved in treatment decisions, with over 40% of patients reporting unsatisfactory communication about treatment alternatives or adverse effects. Barriers to optimal care included inadequate access to specialists, inconsistent monitoring protocols, and a lack of multidisciplinary approaches. Both HCPs and patients highlighted the need for clearer definitions of OCS dependency and enhanced tools for tracking treatment adherence. Discussion: The findings underscore the urgent need for systemic reforms to align clinical practice with guidelines. These include establishing pragmatic definitions for OCS dependency, promoting multidisciplinary care, and leveraging technology for monitoring. Addressing psychosocial factors and empowering patients through education and shared decision-making are also critical.

Indexed as

adherence to therapyasthma managementmultidisciplinary approachOCS dependencyoral corticosteroids (OCS)patient-centered caresevere asthmatreatment guidelines

Identifiers

PMID41158296
PMCPMC12554693

What Socratic holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.