Evidence mapPaperPMID 41158445Full record

ArticleExploratory research in clinical and social pharmacy2025

Assessment of insulin pen injection practices and the effectiveness of pharmacist interventions in improving injection technique among patients with diabetes mellitus.

Bidur Sharma, Devindra Kumar Neupane, Rahi Bikram Thapa, Rajani Shakya, Rojeena Koju Shrestha, Pooja Rimal

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Article in Exploratory research in clinical and social pharmacy, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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5 · Who and what money

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6 authors.

Bidur SharmaDepartment of Pharmacy, School of Science, Kathmandu University, Dhulikhel, Nepal.
Devindra Kumar NeupaneDepartment of Pharmacy, School of Science, Kathmandu University, Dhulikhel, Nepal.
Rahi Bikram ThapaHospital Development and Medical Services Division, Ministry of Health, Koshi Province, Biratnagar, Morang, Nepal.
Rajani ShakyaDepartment of Pharmacy, School of Science, Kathmandu University, Dhulikhel, Nepal.
Rojeena Koju ShresthaDepartment of Pharmacy, School of Science, Kathmandu University, Dhulikhel, Nepal.
Pooja RimalDepartment of Pharmacy, Purbanchal University School of Health Science, Gothgaun, Morang, Nepal.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Insulin therapy is crucial for Type 1 and advanced Type 2 diabetes management. Despite the convenience of insulin pens, improper use persists due to limited patient education. Pharmacists' expertise in counseling and medication safety uniquely positions them to address these gaps through individualized guidance on use, adherence, and monitoring. Objectives: This study aimed to evaluate the impact of pharmacist-led interventions on improving insulin injection practices among diabetes patients. Methods: A pre-post interventional study was conducted at Dhulikhel Hospital (April-September 2018) among 81 consecutively enrolled insulin pen users (≥12 years; on pens ≥2 weeks) from inpatient and outpatient wards. Patients underwent baseline assessment of 16 injection technique elements, received one-to-one pharmacist-led training with demonstration, and were reassessed immediately and after 2 weeks. The primary outcome was the total technique score (0-16), analyzed using Friedman's test and Wilcoxon signed-rank test. Results: Cold chain maintenance was suboptimal, with 51.9 % of patients transporting insulin cartridges without an icepack. Unsafe needle disposal was common, with 40.7 % discarding needles in municipal vehicles, 13.6 % in bushes, and 4.9 % in rivers. Pharmacist-led interventions significantly improved all practices ( Conclusion: Pharmacist-led education significantly improved insulin injection techniques. Integrating pharmacists into routine diabetes care and reinforcing education is essential to sustain these improvements. These findings underscore that clinical pharmacy interventions make a tangible difference in improving healthcare outcomes.

Indexed as

Clinical pharmacy outcomesDiabetes mellitusInsulin injection practicesNepalPatient educationPharmacist intervention

Identifiers

PMID41158445
PMCPMC12556281

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.