Evidence map›Paper›PMID 41158713›Full record

ArticleMaterials today. Bio2025

RGD-grafted dextran methacrylate hydrogel incorporating osteogenic peptide and Mn

Yuxuan Pang, Xin Wang, Huan Zhang, Xin Li, Min Lin, Liang Cheng, Ying-Wei Yang

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Materials today. Bio, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Yuxuan PangDepartment of Prosthodontics, School and Hospital of Stomatology, Jilin University, Changchun, 130021, PR China.
Xin WangCollege of Chemistry and China-Japan Union Hospital of Jilin University, Jilin University, Changchun, 130012, PR China.
Huan ZhangSchool of Biomedical Sciences, Faculty of Medicine, The Chinese University of Hong Kong, Hong Kong SAR 999077, PR China.
Xin LiCollege of Chemistry and China-Japan Union Hospital of Jilin University, Jilin University, Changchun, 130012, PR China.
Min LinState Key Laboratory of Bio-Fibers and Eco-Textiles, College of Materials Science and Engineering, Qingdao University, Qingdao, 266071, PR China.
Liang ChengDepartment of Prosthodontics, School and Hospital of Stomatology, Jilin University, Changchun, 130021, PR China.
Ying-Wei YangCollege of Chemistry and China-Japan Union Hospital of Jilin University, Jilin University, Changchun, 130012, PR China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Aggressive inflammation triggered by excessive reactive oxygen species (ROS) seriously disrupts intercellular communication between macrophages and tissue regenerative cells, such as bone marrow mesenchymal stem cells (BMSCs) and vascular endothelial cells, thereby delaying the healing process. Modulating the immune microenvironment through biomaterial-based strategies is crucial for effective healing. In this study, we constructed a composite hydrogel (denoted as RGD@DEXMA/DOPA-P24/Mn

Indexed as

Anti-inflammatoryBone defect healingHydrogelImmunoregulationNanozymes

Identifiers

PMID41158713
PMCPMC12554889

What Socratic holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.