Evidence map›Paper›PMID 41159865›Full record

ArticleThe Journal of chemical physics2025

Perspective: An outlook on fluorescence tracking.

Lance W Q Xu, Steve Pressé

Abstract read
In one paragraph

Article in The Journal of chemical physics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors.

Lance W Q XuCenter for Biological Physics, Arizona State University, Tempe, Arizona 85287, USA.ORCID 0000-0002-1413-1007
Steve PresséCenter for Biological Physics, Arizona State University, Tempe, Arizona 85287, USA.ORCID 0000-0002-5408-0718

Funding

Toward high spatiotemporal resolution models of single molecules for in vivo applicationsR35GM148237 · NIGMS · ARIZONA STATE UNIVERSITY-TEMPE CAMPUS · PI Steve Presse · 2023 to 2026
$1.7M
NIGMS NIH HHS R35 GM148237
6 · The paper itself

Abstract

Tracking single fluorescent molecules has provided new insights into dynamic molecular processes at the single-molecule level. This Perspective traces the evolution of single-molecule tracking, highlighting key methodological developments across fluorescence microscopy. In particular, we start by exploring what can be gleaned from each type of data and its resulting tracks, ranging from conventional widefield offline tracking to real-time confocal tracking. We subsequently consider emerging efforts to advance physics-inspired tracking techniques, the potential for parallelization and artificial intelligence, and both challenges and opportunities they present toward achieving higher spatiotemporal resolution as well as greater computational and data efficiency in next-generation single-molecule studies.

Identifiers

PMID41159865
PMCPMC12962784

What Socratic holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.